Evidence map›Paper›PMID 30655564›Full record

ArticleScientific reports2019

Royal jelly peptides: potential inhibitors of β-secretase in N2a/APP695swe cells.

Xueqing Zhang, Yi Yu, Ping Sun, Zhen Fan, Wensheng Zhang, Chengqiang Feng

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
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  5. Royal Jelly: Biological Action and Health Benefits.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xueqing ZhangBeijing Key Laboratory of Protection and Utilization of Chinese Medicine, Beijing Normal University, Beijing, People's Republic of China.
Yi YuBeijing Key Laboratory of Protection and Utilization of Chinese Medicine, Beijing Normal University, Beijing, People's Republic of China.
Ping SunBeijing Key Laboratory of Protection and Utilization of Chinese Medicine, Beijing Normal University, Beijing, People's Republic of China.
Zhen FanBeijing Key Laboratory of Protection and Utilization of Chinese Medicine, Beijing Normal University, Beijing, People's Republic of China.
Wensheng ZhangBeijing Key Laboratory of Protection and Utilization of Chinese Medicine, Beijing Normal University, Beijing, People's Republic of China.
Chengqiang FengBeijing Key Laboratory of Protection and Utilization of Chinese Medicine, Beijing Normal University, Beijing, People's Republic of China. Fengchengqiang@bnu.edu.cn.
Beijing Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Royal jelly (RJ) is a type of natural health product with a long history of use. Royal jelly peptides (RJPs) obtained from RJ have numerous bioactivities. To study the neuroprotective effect of RJPs, major royal jelly proteins were digested into crude RJPs and subsequently purified by RP-HPLC. Purified RJP fractions were evaluated in N2a/APP695swe cells. Our results indicated that purified royal jelly peptides (RJPs) (1-9 μg/mL) could inhibit external beta-amyloid 40 (Aβ

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAmyloid Precursor Protein SecretasesAnimalsCell Line, TumorFatty AcidsNeuroprotective AgentsPeptide FragmentsPeptidesRoyal JellyAmyloid beta-Peptidesamyloid beta-protein (1-40)amyloid beta-protein (1-42)Amyloid Precursor Protein SecretasesFatty AcidsNeuroprotective AgentsPeptide FragmentsPeptidesRoyal Jelly

Identifiers

PMID30655564
PMCPMC6336779
OpenAlexW2909893323

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.