Evidence map›Paper›PMID 30655559›Full record

ArticleScientific reports2019

The circadian E3 ligase complex SCF

Stephanie Papp Correia, Alanna B Chan, Megan Vaughan, Norjin Zolboot, Valerie Perea, Anne-Laure Huber, Anna Kriebs, James J Moresco, John R Yates, Katja A Lamia

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 32 citations in OpenAlex.

  1. Hepatocellular Carcinoma Around the Clock.Current oncology (Toronto, Ont.) · 2026
    Review
  2. Article
  3. Review
  4. Chronic CRYPTOCHROME deficiency enhances cell-intrinsic antiviral defences.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
  5. Article
  6. Inhibitors Targeting the F-BOX Proteins.Cell biochemistry and biophysics · 2023
    Review
  7. Article
  8. Review
  9. The molecular clockwork of mammalian cells.Seminars in cell & developmental biology · 2022
    Review
  10. Article
  11. Article
  12. Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  13. Article
  14. Article
  15. Article
  16. Cancer, hear my battle CRY.Journal of pineal research · 2020
    Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Stephanie Papp CorreiaDepartment of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA.
Alanna B ChanDepartment of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA.
Megan VaughanDepartment of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA.ORCID 0000-0002-8289-0638
Norjin ZolbootDepartment of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA.
Valerie PereaDepartment of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA.
Anne-Laure HuberDepartment of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA.
Anna KriebsDepartment of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA.
James J MorescoDepartment of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA.
John R YatesDepartment of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA.ORCID 0000-0001-5267-1672
Katja A LamiaDepartment of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA. klamia@scripps.edu.
Scripps Research Institute · US

Funding

TrainingP41GM103533 · NIGMS · UNIVERSITY OF WASHINGTON · PI MACCOSS, MICHAEL · 2012 to 2021
$20.7M
Impacting Cell Growth through altered circadian proteolysisR01CA211187 · NCI · SCRIPPS RESEARCH INSTITUTE, THE · PI Katja A Lamia · 2017 to 2026
$4.6M
Circadian molecular regulation of the xenobiotic responseR01DK097164 · NIDDK · SCRIPPS RESEARCH INSTITUTE, THE · PI LAMIA, KATJA A · 2013 to 2017
$2.1M
Regulation of exercise physiology by mammalian cryptochromesR01DK112927 · NIDDK · SCRIPPS RESEARCH INSTITUTE, THE · PI LAMIA, KATJA A · 2018 to 2021
$1.7M
NCI NIH HHS R01 CA211187NIDDK NIH HHS R01 DK097164NIDDK NIH HHS R01 DK112927NIGMS NIH HHS P41 GM103533
6 · The paper itself

Abstract

We recently demonstrated that the circadian clock component CRY2 is an essential cofactor in the SCF

Indexed as

AnimalsCells, CulturedCircadian ClocksCryptochromesF-Box ProteinsHumansMiceProtein Serine-Threonine KinasesStem Cell FactorUbiquitin-Protein Ligase ComplexesUbiquitin-Protein LigasesCry1 protein, mouseCry2 protein, mouseCryptochromesF-Box ProteinsFbxl3 protein, mouseKITLG protein, humanProtein Serine-Threonine KinasesStem Cell FactorTlk2 protein, mouseUbiquitin-Protein Ligase ComplexesUbiquitin-Protein Ligases

Identifiers

PMID30655559
PMCPMC6336870
OpenAlexW2911066150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.