Evidence map›Paper›PMID 30655556›Full record

ArticleScientific reports2019

PD-1/PD-L1 Pathway Modulates Macrophage Susceptibility to Mycobacterium tuberculosis Specific CD8

Guadalupe Verónica Suarez, Claudia Del Carmen Melucci Ganzarain, María Belén Vecchione, César Ariel Trifone, José Luis Marín Franco, Melanie Genoula, Eduardo José Moraña, Luciana Balboa, Maria Florencia Quiroga

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Delayed-Type Hypersensitivity toInternational journal of molecular sciences · 2026
    Pooled it
  2. Article
  3. Pathogens (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Landscape of T Cells in Tuberculous Pleural Effusion.The clinical respiratory journal · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. MedComm · 2024
    Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Guadalupe Verónica SuarezConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET)-Universidad de Buenos Aires. Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Buenos Aires, Argentina.
Claudia Del Carmen Melucci GanzarainConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET)-Universidad de Buenos Aires. Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Buenos Aires, Argentina.
María Belén VecchioneConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET)-Universidad de Buenos Aires. Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Buenos Aires, Argentina.ORCID 0000-0002-5408-5922
César Ariel TrifoneConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET)-Universidad de Buenos Aires. Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Buenos Aires, Argentina.
José Luis Marín FrancoConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET)-Instituto de Medicina Experimental (IMEX)-Academia Nacional de Medicina, Buenos Aires, Argentina.
Melanie GenoulaConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET)-Instituto de Medicina Experimental (IMEX)-Academia Nacional de Medicina, Buenos Aires, Argentina.
Eduardo José MorañaInstituto de Tisioneumonologia Dr R. F. Vaccarezza, Universidad de Buenos Aires, Buenos Aires, Argentina.
Luciana BalboaConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET)-Instituto de Medicina Experimental (IMEX)-Academia Nacional de Medicina, Buenos Aires, Argentina.
Maria Florencia QuirogaConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET)-Universidad de Buenos Aires. Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Buenos Aires, Argentina. fquiroga@fmed.uba.ar.ORCID 0000-0002-0956-5492
Consejo Nacional de Investigaciones Científicas y Técnicas · ARAcademia Nacional de Medicina · ARUniversidad de Buenos Aires · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD8

Indexed as

Cell DeathB7-H1 AntigenBlood Specimen CollectionCD8-Positive T-LymphocytesHumansMacrophagesMycobacterium tuberculosisPleural EffusionProgrammed Cell Death 1 ReceptorT-Lymphocytes, CytotoxicTuberculosisB7-H1 AntigenCD274 protein, humanPDCD1 protein, humanProgrammed Cell Death 1 Receptor

Identifiers

PMID30655556
PMCPMC6336852
OpenAlexW2915174466

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.