Evidence map›Paper›PMID 30655500›Full record

ArticleThe American journal of case reports2019

Tracheobronchopathia Osteochondroplastica: A Case Report Illustrating the Importance of Multilevel Workup Clinical, Endoscopic and Histological Assessment in Diagnosis of an Uncommon Disease.

Giulio Riva, Ilaria Girolami, Claudio Luchini, Manuela Villanova, Giovanni Valotto, Luca Cima, Rodolfo Carella, Maurizio Riva, Filippo Fraggetta, Luca Novelli and 1 more

Open access · hybridAbstract readCase Reports
In one paragraph

Article in The American journal of case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. A rare case of tracheobronchopathia osteochondroplastica.Respiratory medicine case reports · 2025
    Article
  3. Article
  4. Clinicopathological Features and Management Principles of Tracheobronchopathia Osteochondroplastica - A Scoping Review.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Giulio RivaPathology Unit, Department of Pathology and Diagnostics, University and Hospital Trust of Verona, Verona, Italy.
Ilaria GirolamiPathology Unit, Department of Pathology and Diagnostics, University and Hospital Trust of Verona, Verona, Italy.
Claudio LuchiniPathology Unit, Department of Pathology and Diagnostics, University and Hospital Trust of Verona, Verona, Italy.
Manuela VillanovaPathology Unit, Department of Pathology and Diagnostics, University and Hospital Trust of Verona, Verona, Italy.
Giovanni ValottoPathology Unit, Department of Pathology and Diagnostics, University and Hospital Trust of Verona, Verona, Italy.
Luca CimaPathology Unit, Department of Pathology and Diagnostics, University and Hospital Trust of Verona, Verona, Italy.
Rodolfo CarellaDepartment of Pathology, Central Hospital of Bolzano, Bolzano, Italy.
Maurizio RivaDepartment of Pathology, Central Hospital of Bolzano, Bolzano, Italy.
Filippo FraggettaDepartment of Pathology, Cannizzaro Hospital, Catania, Italy.
Luca NovelliInstitute of Histopathology and Molecular Diagnosis, Careggi Hospital, Florence, Italy.
Albino EccherPathology Unit, Department of Pathology and Diagnostics, University and Hospital Trust of Verona, Verona, Italy.
University of Verona · ITOspedale di Bolzano · ITOspedale Cannizzaro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Tracheobronchopathia osteochondroplastica (TO) is a rare idiopathic disease with a stable course, which involves the lumen of the tracheobronchial tree. Clinical manifestations at time of presentation may differ, typically including hoarseness, persistent and/or productive cough, hemoptyses, and dyspnea. There are no well-established guidelines for diagnostic workup and treatment. Our aim here is to present a paradigmatic case of TO together with a concise survey of the most important clinical, radiological, and histological criteria. CASE REPORT We report a case of a 62-year-old non-smoker male with persisting cough and no prior history of respiratory disease. Chest radiography (RX) and computed tomography (CT) were unremarkable. Given the persistence of symptoms, the patient underwent bronchoscopic examination, which revealed protruding sessile nodules into the tracheal lumen, with cobblestone appearance. Histopathological examination of biopsies taken during bronchoscopy showed cartilaginous and osseous submucosal nodules consistent with the diagnosis of TO. CONCLUSIONS TO is not always an easily recognized disease, and a multidisciplinary team work is often required for diagnosis, with particular importance of endoscopic-pathological correlation.

Indexed as

BronchoscopyCoughHumansMaleMiddle AgedOsteochondrodysplasiasTracheal Diseases

Identifiers

PMID30655500
PMCPMC6345107
OpenAlexW2909149943

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.