ArticleHaematologica2019
Molecular mechanisms of bleeding disorderassociated GFI1B
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Article in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
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Who cites it
18 citing papers in PubMed, 25 citations in OpenAlex.
- Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review).Oncology reports · 2026Review
- LSD1/KDM1A and GFI1B repress endothelial fate and induce hematopoietic fate in induced pluripotent stem cell-derived hemogenic endothelium.Haematologica · 2024Article
- GFI1B and LSD1 repress myeloid traits during megakaryocyte differentiation.Communications biology · 2024Article
- Thrombotic Alterations under Perinatal Hypoxic Conditions: HIF and Other Hypoxic Markers.International journal of molecular sciences · 2023Review
- Understanding blood development and leukemia using sequencing-based technologies and human cell systems.Frontiers in molecular biosciences · 2023Review
- Article
- Effects of ex vivo blood anticoagulation and preanalytical processing time on the proteome content of platelets.Journal of thrombosis and haemostasis : JTH · 2022Article
- Circular RNAs exhibit limited evidence for translation, or translation regulation of the mRNA counterpart in terminal hematopoiesis.RNA (New York, N.Y.) · 2022Article
- Combined transcriptome and proteome profiling of SRC kinase activity in healthy and E527K defective megakaryocytes.Haematologica · 2021Article
- Platelet proteome and function in X-linked thrombocytopenia with thalassemia andHaematologica · 2021Article
- Thrombocytopenia after meta-iodobenzylguanidine (MIBG) therapy in neuroblastoma patients may be caused by selective MIBG uptake via the serotonin transporter located on megakaryocytes.EJNMMI research · 2021Article
- Dominant negative Gfi1b mutations cause moderate thrombocytopenia and an impaired stress thrombopoiesis associated with mild erythropoietic abnormalities in mice.Haematologica · 2020Article
- Clonal hematopoietic mutations linked to platelet traits and the risk of thrombosis or bleeding.Haematologica · 2020Review
- Role of HDACs in normal and malignant hematopoiesis.Molecular cancer · 2020Review
- Multifaceted Actions of GFI1 and GFI1B in Hematopoietic Stem Cell Self-Renewal and Lineage Commitment.Frontiers in genetics · 2020Review
- Mechanistic and Translational Advances Using iPSC-Derived Blood Cells.Journal of Experimental Pathology · 2020Article
- Inherited missense variants that affect GFI1B function do not necessarily cause bleeding diatheses.Haematologica · 2019Article
- Targeting the GFI1/1B-CoREST Complex in Acute Myeloid Leukemia.Frontiers in oncology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 7 institutions in 2 countries.
Rinske van OorschotDepartment of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen.
Marten HansenDepartment of Hematopoiesis, Sanquin Research-Academic Medical Center Landsteiner Laboratory, Amsterdam.
Johanna M KoornneefDepartment of Plasma Proteins, Sanquin Research, Amsterdam.
Anna E MarnethDepartment of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen.
Saskia M BergevoetDepartment of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen.
Maaike G J M van BergenDepartment of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen.
Floris P J van AlphenDepartment of Research Facilities, Sanquin Research, Amsterdam.
Carmen van der ZwaanDepartment of Plasma Proteins, Sanquin Research, Amsterdam.
Joost H A MartensDepartment of Molecular Biology, Faculty of Science, Radboud University Nijmegen, Radboud Institute for Molecular Life Sciences, Nijmegen.
Michiel VermeulenDepartment of Molecular Biology, Faculty of Science, Radboud University Nijmegen, Radboud Institute for Molecular Life Sciences, Nijmegen.
Pascal W T C JansenDepartment of Molecular Biology, Faculty of Science, Radboud University Nijmegen, Radboud Institute for Molecular Life Sciences, Nijmegen.
Marijke P A BaltissenDepartment of Molecular Biology, Faculty of Science, Radboud University Nijmegen, Radboud Institute for Molecular Life Sciences, Nijmegen.
Britta A P Laros-van GorkomDepartment of Hematology, Radboud University Medical Center, Nijmegen.
Hans JanssenDepartment of Biochemistry, the Netherlands Cancer Institute, Amsterdam, the Netherlands.
Joop H JansenDepartment of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen.
Marieke von LindernDepartment of Hematopoiesis, Sanquin Research-Academic Medical Center Landsteiner Laboratory, Amsterdam.
Alexander B MeijerDepartment of Plasma Proteins, Sanquin Research, Amsterdam.
Emile van den AkkerDepartment of Hematopoiesis, Sanquin Research-Academic Medical Center Landsteiner Laboratory, Amsterdam.
Bert A van der ReijdenDepartment of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen bert.vanderReijden@radboudumc.nl.
Sanquin · NLUniversity Medical Center · USRadboud University Nijmegen · NLRadboud Institute for Molecular Life Sciences · NLRadboud University Medical Center · NLAcademic Medical Center · NLThe Netherlands Cancer Institute · NL
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dominant-negative mutations in the transcription factor Growth Factor Independence-1B (GFI1B), such as GFI1B
Indexed as
Gene Expression RegulationMutationBlood Coagulation DisordersBlood PlateletsCell DifferentiationCo-Repressor ProteinsHistone Deacetylase 1Histone Deacetylase 2Histone DemethylasesHumansInduced Pluripotent Stem CellsMegakaryocytesNerve Tissue ProteinsPhenotypeProtein Interaction MapsProteomeCo-Repressor ProteinsGFI1B protein, humanHDAC1 protein, humanHDAC2 protein, humanHistone Deacetylase 1Histone Deacetylase 2Histone DemethylasesKDM1A protein, humanNerve Tissue ProteinsProteomeProto-Oncogene ProteinsRCOR1 protein, humanRepressor Proteins
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.