ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019
Sensory Representations Supporting Memory Specificity: Age Effects on Behavioral and Neural Discriminability.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Enhanced Contour-Deviant Mismatch Negativity and Mnemonic Representations in Older Musicians.The European journal of neuroscience · 2026Article
- Ventromedial prefrontal cortex supports prototype representations in healthy older adults.Neurobiology of aging · 2026Article
- White-matter connectivity shapes visual and semantic representations in the aging brain.bioRxiv : the preprint server for biology · 2026Article
- Hippocampal connectivity predicting recognition and categorization abilities.Frontiers in cognition · 2026Article
- Adult lifespan effects on functional specialization along the hippocampal long axis.Frontiers in cognition · 2026Article
- Investigating the Cognitive Correlates of Semantic and Perceptual False Memory in Older and Younger Adults: A Multi-Group Latent Variable Approach.Journal of memory and language · 2025Article
- Neural effects of memory training to reduce false memories in older adults: Univariate and multivariate analyses.Neurobiology of aging · 2025Article
- How age and culture impact the neural correlates of memory retrieval.Cognitive, affective & behavioral neuroscience · 2025Article
- Aging and episodic memory specificity: Evidence challenging a domain-general pattern separation decline.PloS one · 2025Article
- Dendritic Spines of Layer 5 Pyramidal Neurons of the Aging Somatosensory Cortex Exhibit Reduced Volumetric Remodeling.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Effects of Age on Cross-Cultural Differences in the Neural Correlates of Memory Retrieval.bioRxiv : the preprint server for biology · 2024Article
- Mnemonic But Not Contextual Feedback Signals Defy Dedifferentiation in the Aging Early Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Representation of shared surface information and false memory for abstract versus concrete pictures in the conjoint recognition paradigm.Psychological research · 2024Article
- Dissociative Effects of Age on Neural Differentiation at the Category and Item Levels.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Demands on perceptual and mnemonic fidelity are a key determinant of age-related cognitive decline throughout the lifespan.Journal of experimental psychology. General · 2024Article
- Memory precision and age differentially predict the use of decision-making strategies across the lifespan.Scientific reports · 2023Article
- Age differences in neural distinctiveness during memory encoding, retrieval, and reinstatement.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- GABA decrease is associated with degraded neural specificity in the visual cortex of glaucoma patients.Communications biology · 2023Article
- Article
- The effects of age on category learning and prototype- and exemplar-based generalization.Psychology and aging · 2022Article
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3 authors.
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Abstract
Older adults' difficulty in distinguishing between old and new information contributes to memory decline, which may occur because older adults are less likely than young adults to retrieve specific sensory details necessary to distinguish between similar items. In male and female human subjects, the present study measured the extent of age differences in the specificity of memory representations using a false memory paradigm in which studied items were linked to retrieval items at multiple levels of similarity. Older adults showed poorer behavioral discrimination than young adults, driven primarily by false recognition of lures that differed from targets only in perceptual details. Patterns of activation across several regions within ventral visual cortex could be used to distinguish between targets and lures when they differed in both perceptual details and a semantic label. However, of ventral visual regions, only signals in the midline occipital cortex could be used to distinguish targets from lures when they differed only in perceptual details. Although there was an overall age deficit for this neural discrimination in this region, the positive relationship between neural and behavioral discriminability did not differ across age groups. In contrast, age moderated the relationship between neural and behavioral discriminability in lateral occipital and fusiform cortices, suggesting that activation patterns within these regions represent different types of information in each age group. Therefore, the quality of perceptual signals is a key contributor to memory discrimination across age groups, with evidence that age differences in the nature of representations emerges outside early visual cortex.
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