ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2019
Automatic Extraction of a Reference Region for the Noninvasive Quantification of Translocator Protein in Brain Using
Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Validating the Utility of Supervised Clustering Algorithm for Precise [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025Article
- Microglial Positron Emission Tomography Imaging In Vivo : Positron Emission Tomography Radioligands: Utility in Research and Clinical Practice.Advances in neurobiology · 2024Review
- Textural properties of microglial activation in Alzheimer's disease as measured by (R)-[Brain communications · 2023Article
- Image Quantification for TSPO PET with a Novel Image-Derived Input Function Method.Diagnostics (Basel, Switzerland) · 2022Article
- Supervised clustering for TSPO PET imaging.European journal of nuclear medicine and molecular imaging · 2021Review
- Parametric Mapping for TSPO PET Imaging with Spectral Analysis Impulsive Response Function.Molecular imaging and biology · 2021Article
- Microglial activation, but not tau pathology, is independently associated with amyloid positivity and memory impairment.Neurobiology of aging · 2020Article
- Patterns of Mitochondrial TSPO Binding in Cerebral Small Vessel Disease: AnFrontiers in neurology · 2020Article
- Association of neuroinflammation with episodic memory: a [Brain communications · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brain inflammation is associated with various types of neurodegenerative diseases, including Alzheimer disease (AD). Quantifying inflammation with PET is a challenging and invasive procedure, especially in frail patients, because it requires blood sampling from an arterial catheter. A widely used alternative to arterial sampling is a supervised clustering algorithm (SVCA), which identifies the voxels with minimal specific binding in the PET images, thus extracting a reference region for noninvasive kinetic modeling.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.