Evidence map›Paper›PMID 30655057›Full record

ReviewTrends in parasitology2019

Sensing What's Out There - Kinetoplastid Parasites.

Scott M Landfear, Dan Zilberstein

Abstract readReview
In one paragraph

Review in Trends in parasitology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Lysosome Sensing Is a Key Mechanism inFrontiers in microbiology · 2021
    Review
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Scott M LandfearDepartment of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, OR, USA. Electronic address: landfear@ohsu.edu.
Dan ZilbersteinFaculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel.

Funding

Function of the Essential KHARON1 Protein in Bloodstream Form African TrypanosomesR01AI121160 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI LANDFEAR, SCOTT M · 2016 to 2020
$2.6M
The Role of the Kharon Complex in Leishmania VirulenceR21AI114822 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI LANDFEAR, SCOTT M · 2015 to 2016
$424k
Development of Drugs that Target the Malaria Hexose TransporterR21AI114842 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI LANDFEAR, SCOTT M · 2015 to 2016
$424k
NIAID NIH HHS R01 AI121160NIAID NIH HHS R21 AI114822NIAID NIH HHS R21 AI114842
6 · The paper itself

Abstract

Kinetoplastid parasites such as trypanosomes and Leishmania must adapt to their environments to survive within their hosts, yet they do not express many of the well established families of signal transduction receptors. Evidence suggests that other membrane proteins, including transporters and channels, play central roles in environmental sensing in these parasites.

Indexed as

EnvironmentAdaptation, PhysiologicalKinetoplastidaMembrane ProteinsMembrane Proteinschannelsenvironmental sensingkinetoplastid parasitesreceptor-adenylate cyclasestransporters

Identifiers

PMID30655057
PMCPMC7392150

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.