Evidence map›Paper›PMID 30654836›Full record

ArticleInfectious diseases of poverty2019

Prevalence and risk factors of active pulmonary tuberculosis among elderly people in China: a population based cross-sectional study.

Can-You Zhang, Fei Zhao, Yin-Yin Xia, Yan-Ling Yu, Xin Shen, Wei Lu, Xiao-Meng Wang, Jin Xing, Jian-Jun Ye, Jian-Wei Li and 6 more

Open access · goldAbstract read
In one paragraph

Article in Infectious diseases of poverty, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.

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  18. Ending Tuberculosis in Older People: New Strategies for an Age-old Disease.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 1 country.

Can-You ZhangNational Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Fei ZhaoNational Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Yin-Yin XiaNational Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Yan-Ling YuHeilongjiang Provincial Center for Tuberculosis Control and Prevention, Harbin, Heilongjiang, China.
Xin ShenShanghai Municipal Center for Disease Control and Prevention, Shanghai, China.
Wei LuJiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu, China.
Xiao-Meng WangZhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
Jin XingHenan Provincial Center for Disease Control and Prevention, Zhengzhou, Henan, China.
Jian-Jun YeHubei Provincial Center for Disease Control and Prevention, Wuhan, Hubei, China.
Jian-Wei LiCenter for Tuberculosis Control of Guangdong Province, Guangzhou, Guangdong, China.
Fei-Ying LiuGuangxi Provincial Center for Disease Control and Prevention, Nanning, Guangxi, China.
Jian-Lin WuSichuan Provincial Center for Disease Control and Prevention, Chengdu, Sichuan, China.
Lin XuYunnan Provincial Center for Disease Control and Prevention, Kunming, Yunnan, China.
Hui ZhangNational Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China. zhanghui@chinacdc.cnl.
Jun ChengNational Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China. chengjun@chinacdc.cn.
Li-Xia WangNational Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China. wanglx@chinacdc.cn.
Chinese Center For Disease Control and Prevention · CNCenter for Tuberculosis Control of Guangdong Province · CNGuangxi Center for Disease Prevention and Control · CNHeilongjiang Center for Tuberculosis Control and Prevention · CNHenan Provincial Center for Disease Control and Prevention · CNHubei Provincial Center for Disease Control and Prevention · CNJiangsu Provincial Center for Disease Control and Prevention · CNShanghai Municipal Center For Disease Control Prevention · CNSichuan Center for Disease Control and Prevention · CNYunnan Center for Disease Control And Prevention · CNZhejiang Center for Disease Control and Prevention · CN

Funding

Mega-scientific projects of AIDS, viral hepatitis and other major infectious diseases 2013ZX10003004-001
6 · The paper itself

Abstract

backgroundThe problem of population aging is a critical public health concern in modern China, and more tuberculosis (TB) control efforts are needed to reach elderly people at high priority. In this study, we aim to determine the prevalence and identify the risk factors of TB among elderly people in China.

methodsA multistage cluster-sampled cross-sectional survey was conducted in 2013, and 27 clusters were selected from 10 counties of 10 provinces in China. All consenting participants greater than or equal to 65 years of age were screened for pulmonary TB with a chest X-ray (CXR) and a symptom questionnaire. Three sputum specimens for bacteriological examination by microscopy and culture were collected from those whose screening was positive. Prevalence was calculated, a multiple logistic regression model was performed to confirm the risk factors, and population attributable fraction (PAF) of each risk factor was calculated to indicate the public health significance.

resultsOf 38 888 eligible people from 27 clusters, 34 269 participants finished both questionnaire and physical examination. There were 193 active pulmonary TB cases, 62 of which were bacteriologically confirmed. The estimated prevalence of active pulmonary TB and bacteriologically confirmed TB in those 65 years of age and older was 563.19 per 100 000 (95% CI: 483.73-642.65) and 180.92 per 100 000 (95% CI: 135.89-225.96), respectively. Male sex, older age, living in rural areas, underweight, diabetes, close contact of pulmonary TB (PTB) and previous TB history are all risk factors for TB. The risk of TB increased with increasing age and decreasing body mass index (BMI) after adjusting for other factors, and there is a positive dose-response relationship.

conclusionsIn China, active case finding (ACF) could be implemented among elderly people aged 65 and above with underweight, diabetes, close contact history and previous TB history as a priority, which will get significant yields and be cost-effective.

Indexed as

AgedAged, 80 and overAlgorithmsChinaCross-Sectional StudiesFemaleHumansMaleMass ScreeningPrevalenceRisk FactorsTuberculosis, PulmonaryAged/elderlyPrevalencePulmonary tuberculosisRisk factor

Identifiers

PMID30654836
PMCPMC6337869
OpenAlexW2909017651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.