Evidence map›Paper›PMID 30654769›Full record

ArticleBMC pulmonary medicine2019

Bacteriologically confirmed extra pulmonary tuberculosis and treatment outcome of patients consulted and treated under program conditions in the littoral region of Cameroon.

Teyim Pride Mbuh, Irene Ane-Anyangwe, Wandji Adeline, Benjamin D Thumamo Pokam, Henry Dilonga Meriki, Wilfred Fon Mbacham

Abstract read
In one paragraph

Article in BMC pulmonary medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Medicinal Plants in the Treatment of Tuberculosis: A Systematic Review.Central nervous system agents in medicinal chemistry · 2025
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  14. Obstructive Jaundice Secondary to Hepatic Hilar Tuberculosis Without Pulmonary Involvement.European journal of case reports in internal medicine · 2024
    Article
  15. Comparative Diagnostic of Cervical Tuberculous Lymphadenitis: PCR is a Fast, Efficient, and Improved Diagnostic Approach.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023
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  20. Oxford medical case reports · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Teyim Pride MbuhDepartment of Microbiology and Parasitology, Faculty of Science, University of Buea, Buea, Cameroon. teyimpride@yahoo.com.ORCID http://orcid.org/0000-0002-0593-6831
Irene Ane-AnyangweDepartment of Microbiology and Parasitology, Faculty of Science, University of Buea, Buea, Cameroon.
Wandji AdelineTuberculosis Reference Laboratory, Douala, Littoral Region, Cameroon.
Benjamin D Thumamo PokamDepartment of Medical Laboratory Science, Faculty Health Sciences, University of Buea, Buea, Cameroon.
Henry Dilonga MerikiDepartment of Microbiology and Parasitology, Faculty of Science, University of Buea, Buea, Cameroon.
Wilfred Fon MbachamLaboratory for Public Health Research Biotechnologies, Biotechnology Centre, University of Yaoundé, Yaoundé, Cameroon.

Funding

Notapplicable Not Applicable
6 · The paper itself

Abstract

backgroundExtra-pulmonary tuberculosis (EPTB) is defined as any bacteriologically confirmed or clinically diagnosed case of TB involving organs other than the lungs. It is frequently a diagnostic and therapeutic challenge with paucity of data available. The aim of this study was to assess the prevalence of bacteriologically confirmed EPTB; to determine the most affected organs and to evaluate the therapeutic outcome of EPTB patients treated under program conditions in the littoral region of Cameroon.

methodsA descriptive cross-sectional laboratory-based epidemiological survey was conducted from January 2016 to December 2017 and 109 specimens from 15 of the 39 diagnosis and treatment centers in the littoral region were obtained. Two diagnostic methods (Gene Xpert MTB and culture (LJ and MGIT) were used for EPTB diagnosis. Determine HIV1/2 and SD Biolinewere used for HIV diagnosis. Confirmed EPTB cases were treated following the national tuberculosis guide.

resultsThe prevalence of bacteriologically confirmed EPTB was 41.3% (45). All 45 cases were sensitive to rifampicin. Males were predominately more infected [26 (57.8%)] likewise the age group 31-45 years with 15 (33.3%) cases. The overall prevalence for HIV was 33.6% (36). HIV infection was present in 28.9% (13) of patients with EPTB. The most affected sites with EPTB were: Lymph nodes (66.5%), pleural cavity (15.6%), abdominal organs (11.1%), neuromeningeal (2.2%), joints (2.2%) and heart (2.2%). Overall, 84.4% of the study participants had a therapeutic success with males responding better 57.9% (p = 0.442). Therapeutic success was better (71.7%) in HIV negative EPTB patients (p = 0.787).

conclusionThe prevalence of bacteriologically confirmed EPTB patients treated under program conditions in the littoral region of Cameroon is high with a therapeutic success of 84.4% and the lymph nodes is the most affected site.

Indexed as

AdolescentAdultAntitubercular AgentsCameroonCoinfectionCross-Sectional StudiesDrug Resistance, BacterialFemaleHIV InfectionsHumansMaleMiddle AgedMolecular Diagnostic TechniquesPrevalenceRifampinSex FactorsAntitubercular AgentsRifampinExtra pulmonary TBGene xpert MTB/RIFLittoral region CameroonTreatment outcome

Identifiers

PMID30654769
PMCPMC6337766

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.