ArticleBMC microbiology2019
Comparative study of vulva and abdominal skin microbiota of healthy females with high and average BMI.
Article in BMC microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Decoding the microbial landscape of endometrial cancer: a case-control study.BMC microbiology · 2026Article
- Article
- Obesity, skin disorders, and the microbiota: Unraveling a complex web.Journal of microbiology (Seoul, Korea) · 2026Review
- Vulvar Care: Reviewing Concepts in Daily Hygiene.Healthcare (Basel, Switzerland) · 2025Review
- BodyMeta: A comprehensive database for microbes under various pathological and physiological conditions.Computational and structural biotechnology journal · 2025Article
- Taxonomic and functional profiling of the vulvar microbiome indicates variations related to ecological signatures, aging, and health status.Frontiers in microbiology · 2025Article
- Comparison of extracellular vesicles carrying bacterial DNA in urine and serum from a Korean population.Frontiers in microbiology · 2025Article
- Facial Physiological Characteristics and Skin Microbiomes Changes are Associated with Body Mass Index (BMI).Clinical, cosmetic and investigational dermatology · 2024Article
- The intratumour microbiota and neutrophilic inflammation in squamous cell vulvar carcinoma microenvironment.Journal of translational medicine · 2023Article
- Characterisation of human milk bacterial DNA profiles in a small cohort of Australian women in relation to infant and maternal factors.PloS one · 2023Article
- Necrotizing fasciitis arising from squamous cell carcinoma of the vulva.Dermatology reports · 2022Article
- Analysis of the Vulvar Skin Microbiota in Asymptomatic Women and Patients With Vulvar Lichen Sclerosus Based on 16S rRNA Sequencing.Frontiers in cell and developmental biology · 2022Article
- The Human Vulvar Microbiome: A Systematic Review.Microorganisms · 2021Review
- The Association Between Body Mass Index and the Risk of Hospitalization and Mortality due to Infection: A Prospective Cohort Study.Open forum infectious diseases · 2021Article
- Obesity and ethnicity alter gene expression in skin.Scientific reports · 2020Article
- Toward Standards in Clinical Microbiota Studies: Comparison of Three DNA Extraction Methods and Two Bioinformatic Pipelines.mSystems · 2020Article
- Microbiome in Healthy Women Between Two Districts With Different Air Quality Index.Frontiers in microbiology · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObesity is known to modulate human health in a number of ways including altering the microbiome of the gut. Very few studies have examined the how obesity may affect the microbiomes of sites distant to the gut. We hypothesized that vulva and abdominal skin may be especially susceptible to body mass index (BMI)-induced alterations in biophysical properties and the microbiome due increased maceration and skin folds at those sites. The aim of this study was to determine if high BMI (≥30) was associated with alterations in the biophysical properties and microbiomes of vulva and abdominal skin.
resultsThe vulvar microbial communities of healthy reproductive-aged females were examined using 16S rRNA sequencing techniques. Our results show that vulvar pH of women with high body mass index (BMI) was statistically higher than that of women with average BMI. Phylogenetic analysis of the vulvar microbiota indicated that women with average BMI have a predominately Lactobacillus-dominated flora, whereas women with high BMI and higher pH were predominately colonized by Finegoldia and Corynebacterium. This BMI-associated shift in microbiota was not observed in samples collected from the exposed skin around the belly, indicating the effect is not global.
conclusionThese results indicate that physiological changes associated with changes in BMI may modulate the vulva microbiome.
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