Evidence map›Paper›PMID 30654735›Full record

ArticleGenetics, selection, evolution : GSE2019

Accuracy of imputation to whole-genome sequence in sheep.

Sunduimijid Bolormaa, Amanda J Chamberlain, Majid Khansefid, Paul Stothard, Andrew A Swan, Brett Mason, Claire P Prowse-Wilkins, Naomi Duijvesteijn, Nasir Moghaddar, Julius H van der Werf and 2 more

Abstract readEvaluation Study
In one paragraph

Article in Genetics, selection, evolution : GSE, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  12. Genotype imputation for soybean nested association mapping population to improve precision of QTL detection.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022
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  19. Imputation accuracy to whole-genome sequence in Nellore cattle.Genetics, selection, evolution : GSE · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sunduimijid BolormaaAgriculture Victoria, AgriBio, Centre for AgriBioscience, 5 Ring Rd, Bundoora, VIC, 3083, Australia. bolormaa.sunduimijid@ecodev.vic.gov.au.
Amanda J ChamberlainAgriculture Victoria, AgriBio, Centre for AgriBioscience, 5 Ring Rd, Bundoora, VIC, 3083, Australia.
Majid KhansefidAgriculture Victoria, AgriBio, Centre for AgriBioscience, 5 Ring Rd, Bundoora, VIC, 3083, Australia.
Paul StothardFaculty of Agricultural, Life and Environmental Sciences, University of Alberta, Edmonton, AB, T6G 2R3, Canada.
Andrew A SwanCooperative Research Centre for Sheep Industry Innovation, Armidale, NSW, 2351, Australia.
Brett MasonAgriculture Victoria, AgriBio, Centre for AgriBioscience, 5 Ring Rd, Bundoora, VIC, 3083, Australia.
Claire P Prowse-WilkinsAgriculture Victoria, AgriBio, Centre for AgriBioscience, 5 Ring Rd, Bundoora, VIC, 3083, Australia.
Naomi DuijvesteijnCooperative Research Centre for Sheep Industry Innovation, Armidale, NSW, 2351, Australia.
Nasir MoghaddarCooperative Research Centre for Sheep Industry Innovation, Armidale, NSW, 2351, Australia.
Julius H van der WerfCooperative Research Centre for Sheep Industry Innovation, Armidale, NSW, 2351, Australia.
Hans D DaetwylerAgriculture Victoria, AgriBio, Centre for AgriBioscience, 5 Ring Rd, Bundoora, VIC, 3083, Australia.
Iona M MacLeodAgriculture Victoria, AgriBio, Centre for AgriBioscience, 5 Ring Rd, Bundoora, VIC, 3083, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe use of whole-genome sequence (WGS) data for genomic prediction and association studies is highly desirable because the causal mutations should be present in the data. The sequencing of 935 sheep from a range of breeds provides the opportunity to impute sheep genotyped with single nucleotide polymorphism (SNP) arrays to WGS. This study evaluated the accuracy of imputation from SNP genotypes to WGS using this reference population of 935 sequenced sheep.

resultsThe accuracy of imputation from the Ovine Infinium

conclusionsThe mean imputation accuracy was high for all target breeds and was increased by combining smaller breed sets into a multi-breed reference. We found that the Minimac3 software imputation quality statistic (R

Indexed as

AnimalsGenome-Wide Association StudyPolymorphism, Single NucleotideSheepSoftwareWhole Genome Sequencing

Identifiers

PMID30654735
PMCPMC6337865

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.