Evidence map›Paper›PMID 30654648›Full record

ArticleJournal of diabetes science and technology2019

Improving Glucose Prediction Accuracy in Physically Active Adolescents With Type 1 Diabetes.

Nicole Hobbs, Iman Hajizadeh, Mudassir Rashid, Kamuran Turksoy, Marc Breton, Ali Cinar

Open access · bronzeAbstract read
In one paragraph

Article in Journal of diabetes science and technology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Nicole Hobbs1 Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, USA.
Iman Hajizadeh2 Department of Chemical Engineering, Illinois Institute of Technology, Chicago, IL, USA.
Mudassir Rashid2 Department of Chemical Engineering, Illinois Institute of Technology, Chicago, IL, USA.
Kamuran Turksoy1 Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, USA.
Marc Breton3 Center for Diabetes Technology, University of Virginia, Charlottesville, VA, USA.
Ali Cinar1 Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, USA.
Illinois Institute of Technology · USUniversity of Virginia · US

Funding

Models, signals, and distributed bio-behavioral control of exercise in diabetesDP3DK106826 · NIDDK · UNIVERSITY OF VIRGINIA · PI BRETON, MARC D · 2015 to 2015
$3.0M
Control Systems for Artificial Pancreas Use During and After ExerciseDP3DK101075 · NIDDK · ILLINOIS INSTITUTE OF TECHNOLOGY · PI CINAR, ALI · 2013 to 2013
$2.5M
Fault-tolerant Control Systems for Artificial PancreasDP3DK101077 · NIDDK · ILLINOIS INSTITUTE OF TECHNOLOGY · PI CINAR, ALI · 2013 to 2013
$2.0M
NIDDK NIH HHS DP3 DK101075NIDDK NIH HHS DP3 DK101077NIDDK NIH HHS DP3 DK106826
6 · The paper itself

Abstract

backgroundPhysical activity presents a significant challenge for glycemic control in individuals with type 1 diabetes. As accurate glycemic predictions are key to successful automated decision-making systems (eg, artificial pancreas, AP), the inclusion of additional physiological variables in the estimation of the metabolic state may improve the glucose prediction accuracy during exercise.

methodsPredictor-based subspace identification is applied to a dynamic glucose prediction model including heart rate measurements along with variables representing the carbohydrate consumption and insulin boluses. To demonstrate the improvement in prediction ability due to the additional heart rate variable, the performance of the proposed modeling technique is evaluated with (SID-HR) and without heart rate (SID-2) as an additional input using experimental data involving adolescents at ski camp. Furthermore, the performance of the proposed approach is compared to that of the metabolic state observer (MSO) model currently used in the University of Virginia AP algorithm.

resultsThe addition of heart rate in the subspace-based model (SID-HR) yields a statistically significant improvement in the root-mean-square error compared to the SID-2 model (

conclusionsDirectly considering the effects of physical activity levels on glycemic dynamics through the inclusion of heart rate as an additional input variable in the glucose dynamics model improves the glucose prediction accuracy. The proposed methodology could improve exercise-informed model-based predictive control algorithms in artificial pancreas systems.

Indexed as

AlgorithmsPancreas, ArtificialAdolescentBlood GlucoseBlood Glucose Self-MonitoringDiabetes Mellitus, Type 1ExerciseFemaleHeart RateHumansMaleModels, TheoreticalBlood Glucoseartificial pancreasglucose concentration predictionheart rate informationphysical activitysubspace identification

Identifiers

PMID30654648
PMCPMC6610614
OpenAlexW2910336590

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.