Evidence map›Paper›PMID 30654596›Full record

ReviewViruses2019

Monitoring HIV-1 Assembly in Living Cells: Insights from Dynamic and Single Molecule Microscopy.

Kaushik Inamdar, Charlotte Floderer, Cyril Favard, Delphine Muriaux

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
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  3. Review
  4. Article
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  8. Article
  9. Virus morphology: Insights from super-resolution fluorescence microscopy.Biochimica et biophysica acta. Molecular basis of disease · 2022
    Review
  10. Article
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kaushik InamdarIRIM, CNRS UMR9004, CNRS & University of Montpellier, 34293 Montpellier, France. kaushik.inamdar@irim.cnrs.fr.
Charlotte FlodererIRIM, CNRS UMR9004, CNRS & University of Montpellier, 34293 Montpellier, France. charlotte.floderer@orange.fr.
Cyril FavardIRIM, CNRS UMR9004, CNRS & University of Montpellier, 34293 Montpellier, France. cyril.favard@irim.cnrs.fr.
Delphine MuriauxIRIM, CNRS UMR9004, CNRS & University of Montpellier, 34293 Montpellier, France. delphine.muriaux@irim.cnrs.fr.
Centre National de la Recherche Scientifique · FRUniversité de Montpellier · FR

Funding

Agence Nationale de Recherches sur le Sida et les Hépatites Virales ECTZ37578
6 · The paper itself

Abstract

The HIV-1 assembly process is a multi-complex mechanism that takes place at the host cell plasma membrane. It requires a spatio-temporal coordination of events to end up with a full mature and infectious virus. The molecular mechanisms of HIV-1 assembly have been extensively studied during the past decades, in order to dissect the respective roles of the structural and non-structural viral proteins of the viral RNA genome and of some host cell factors. Nevertheless, the time course of HIV-1 assembly was observed in living cells only a decade ago. The very recent revolution of optical microscopy, combining high speed and high spatial resolution, in addition to improved fluorescent tags for proteins, now permits study of HIV-1 assembly at the single molecule level within living cells. In this review, after a short description of these new approaches, we will discuss how HIV-1 assembly at the cell plasma membrane has been revisited using advanced super resolution microscopy techniques and how it can bridge the study of viral assembly from the single molecule to the entire host cell.

Indexed as

Single Molecule ImagingVirus AssemblyCell LineHIV-1HumansMicroscopy, FluorescenceMolecular Dynamics SimulationRNA, ViralVirionRNA, ViraldynamicsHIV assemblySMLM

Identifiers

PMID30654596
PMCPMC6357049
OpenAlexW2902112107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.