Evidence map›Paper›PMID 30654595›Full record

ArticleInternational journal of molecular sciences2019

Investigation of the Prognostic Role of Carbonic Anhydrase 9 (CAIX) of the Cellular mRNA/Protein Level or Soluble CAIX Protein in Patients with Oral Squamous Cell Carcinoma.

Alexander W Eckert, Susanne Horter, Daniel Bethmann, Johanna Kotrba, Tom Kaune, Swetlana Rot, Matthias Bache, Udo Bilkenroth, Waldemar Reich, Thomas Greither and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  5. Metabolic biomarker in oral squamous cell carcinoma - a comprehensive review.GMS Interdisciplinary plastic and reconstructive surgery DGPW · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Alexander W EckertDepartment of Oral and Maxillofacial Plastic Surgery, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. alexander.eckert@uk-halle.de.
Susanne HorterDepartment of Oral and Maxillofacial Plastic Surgery, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. susanne.horter@uk-halle.de.
Daniel BethmannInstitute of Pathology, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. daniel.bethmann@uk-halle.de.ORCID 0000-0002-9582-025X
Johanna KotrbaDepartment of Oral and Maxillofacial Plastic Surgery, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. johanna.kotrba@med.ovgu.de.
Tom KauneDepartment of Oral and Maxillofacial Plastic Surgery, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. tom.kaune@uk-halle.de.
Swetlana RotDepartment of Oral and Maxillofacial Plastic Surgery, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. swetlana.rot@medizin.uni-halle.de.
Matthias BacheDepartment of Radiotherapy, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. matthias.bache@uk-halle.de.
Udo BilkenrothInstitute of Pathology, 06295 Eisleben, Germany. udobilkenroth@gmx.de.
Waldemar ReichDepartment of Oral and Maxillofacial Plastic Surgery, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. waldemar.reich@uk-halle.de.
Thomas GreitherCenter for Reproductive Medicine and Andrology, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. thomas.greither@medizin.uni-halle.de.ORCID 0000-0002-1888-7813
Claudia WickenhauserInstitute of Pathology, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. claudia.wickenhauser@uk-halle.de.
Dirk VordermarkDepartment of Radiotherapy, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. dirk.vordermark@uk-halle.de.
Helge TaubertClinic of Urology and Pediatric Urology, FA University Hospital Erlangen-Nürnberg, 91054 Erlangen, Germany. Helge.Taubert@uk-erlangen.de.ORCID 0000-0002-9077-1727
Matthias KapplerDepartment of Oral and Maxillofacial Plastic Surgery, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. matthias.kappler@uk-halle.de.ORCID 0000-0003-2002-0271
Martin Luther University Halle-Wittenberg · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

Wilhelm Sander Stiftung FKZ:2013.090.1
6 · The paper itself

Abstract

s

Indexed as

Antigens, NeoplasmBiomarkers, TumorCarbonic Anhydrase IXCarcinoma, Squamous CellFemaleGene Expression Regulation, NeoplasticHumansMaleMouth NeoplasmsMultivariate AnalysisPrognosisProportional Hazards ModelsRNA, MessengerSolubilitySurvival AnalysisAntigens, NeoplasmBiomarkers, TumorCA9 protein, humanCarbonic Anhydrase IXRNA, MessengerCA9CAIXcarbonic anhydrase IXhypoxiaOSCCsurvival

Identifiers

PMID30654595
PMCPMC6359351
OpenAlexW2909113443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.