Evidence map›Paper›PMID 30654589›Full record

ArticleMarine drugs2019

Molecular Networking Reveals Two Distinct Chemotypes in Pyrroloiminoquinone-Producing Tsitsikamma favus Sponges.

Jarmo-Charles J Kalinski, Samantha C Waterworth, Xavier Siwe Noundou, Meesbah Jiwaji, Shirley Parker-Nance, Rui W M Krause, Kerry L McPhail, Rosemary A Dorrington

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The unique and enigmatic spirochete symbiont of latrunculid sponges.bioRxiv : the preprint server for biology · 2024
    Article
  5. Naturally Occurring Organohalogen Compounds-A Comprehensive Review.Progress in the chemistry of organic natural products · 2023
    Review
  6. Review
  7. Marine Pyrrole Alkaloids.Marine drugs · 2021
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Jarmo-Charles J KalinskiDepartment of Biochemistry and Microbiology, Rhodes University, PO Box 94, Grahamstown 6140, South Africa. j.kalinski@gmx.de.
Samantha C WaterworthDepartment of Biochemistry and Microbiology, Rhodes University, PO Box 94, Grahamstown 6140, South Africa. samche42@gmail.com.ORCID 0000-0001-6436-0142
Xavier Siwe NoundouDepartment of Biochemistry and Microbiology, Rhodes University, PO Box 94, Grahamstown 6140, South Africa. X.SiweNoundou@ru.ac.za.ORCID 0000-0002-8667-8351
Meesbah JiwajiDepartment of Biochemistry and Microbiology, Rhodes University, PO Box 94, Grahamstown 6140, South Africa. m.jiwaji@ru.ac.za.ORCID 0000-0003-3557-4541
Shirley Parker-NanceDepartment of Biochemistry and Microbiology, Rhodes University, PO Box 94, Grahamstown 6140, South Africa. shirley@saeon.ac.za.ORCID 0000-0003-4231-6313
Rui W M KrauseDepartment of Chemistry, Rhodes University PO Box 94, Grahamstown 6140, South Africa. r.krause@ru.ac.za.
Kerry L McPhailDepartment of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis 97331, OR, USA. kerry.mcphail@oregonstate.edu.ORCID 0000-0003-2076-1002
Rosemary A DorringtonDepartment of Biochemistry and Microbiology, Rhodes University, PO Box 94, Grahamstown 6140, South Africa. r.dorrington@ru.ac.za.ORCID 0000-0002-8694-367X
Rhodes University · ZAOregon State University · USUniversity of Wisconsin–Madison · US

Funding

Natural Product Drug Discovery from South African Tunicates by Leveraging International Training OpportunitiesR15GM122016 · NIGMS · OREGON STATE UNIVERSITY · PI MCPHAIL, KERRY LEIGH · 2017 to 2017
$405k
NIGMS NIH HHS R15 GM122016
6 · The paper itself

Abstract

The temperate marine sponge,

Indexed as

AnimalsAntimetabolites, AntineoplasticBiosynthetic PathwaysCell SurvivalChromatography, High Pressure LiquidDNADNA Topoisomerases, Type IEnzyme AssaysHEK293 CellsHeLa CellsHumansIntercalating AgentsMolecular StructurePoriferaPyrroloiminoquinonesTandem Mass SpectrometryAntimetabolites, AntineoplasticDNADNA Topoisomerases, Type IIntercalating AgentsPyrroloiminoquinonesTOP1 protein, humanTopoisomerase I InhibitorsdamironediscorhabdinGNPSHR-ESI-LC-MS/MSLatrunculiidaemakaluvamine Qpyrrolo-ortho-quinonepyrroloquinolinetsitsikammamine

Identifiers

PMID30654589
PMCPMC6356464
OpenAlexW2910633965

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.