Evidence map›Paper›PMID 30654483›Full record

ArticleMolecules (Basel, Switzerland)2019

Identification, Characterization, and Optimization of Integrin α

Yng Sarah C Tang, Ryan A Davis, Tanushree Ganguly, Julie L Sutcliffe

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yng Sarah C TangDepartment of Internal Medicine, Division of Hematology/Oncology, University of California, Davis and Sacramento, CA 95817, USA. yngtang@ucdavis.edu.ORCID 0000-0001-6955-1896
Ryan A DavisDepartment of Biomedical Engineering, University of California, Davis, CA 95616, USA. rydavis@ucdavis.edu.ORCID 0000-0002-0638-870X
Tanushree GangulyDepartment of Internal Medicine, Division of Hematology/Oncology, University of California, Davis and Sacramento, CA 95817, USA. tganguly@ucdavis.edu.
Julie L SutcliffeDepartment of Internal Medicine, Division of Hematology/Oncology, University of California, Davis and Sacramento, CA 95817, USA. jlsutcliffe@ucdavis.edu.ORCID 0000-0002-5485-4082
University of California, Davis · US

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI KC KENT LLOYD · 2002 to 2026
$84.9M
National Institutes of Health RO1CA199725-01NCI NIH HHS P30 CA093373Office of Science DE-SC0008385
6 · The paper itself

Abstract

The current translation of peptides identified through the one-bead one-compound (OBOC) technology into positron emission tomography (PET) imaging agents is a slow process, with a major delay between ligand identification and subsequent lead optimization. This work aims to streamline the development process of

Indexed as

Amino Acid SequenceAntigens, NeoplasmCell LineCombinatorial Chemistry TechniquesFluorine RadioisotopesHumansIntegrinsMolecular ImagingPeptide LibraryPeptidesPositron-Emission TomographyAntigens, NeoplasmFluorine-18Fluorine Radioisotopesintegrin alphavbeta6IntegrinsPeptide LibraryPeptidesaffinityFluorine-18integrin αvβ6library screeningone-bead one-compound (OBOC)positron emission tomography (PET)selectivitysolid-phase radiolabeling

Identifiers

PMID30654483
PMCPMC6359284
OpenAlexW2911010519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.