Evidence map›Paper›PMID 30654471›Full record

Trial reportNutrients2019

Validity of an Abbreviated, Clinically Feasible Test for Postprandial Lipemia in Healthy Adults: A Randomized Cross-Over Study.

Christina M Sciarrillo, Nicholas A Koemel, Stephanie P Kurti, Sam R Emerson

Open access · goldAbstract readRandomized Controlled TrialValidation Study
In one paragraph

Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Who would benefit most from postprandial lipid screening?Clinical nutrition (Edinburgh, Scotland) · 2021
    Article
  8. Mechanisms of Atherosclerosis Induced by Postprandial Lipemia.Frontiers in cardiovascular medicine · 2021
    Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Christina M SciarrilloDepartment of Nutritional Sciences, Oklahoma State University, Stillwater, OK 74078, USA. christina.sciarrillo@okstate.edu.
Nicholas A KoemelDepartment of Nutritional Sciences, Oklahoma State University, Stillwater, OK 74078, USA. nick.koemel@okstate.edu.
Stephanie P KurtiDepartment of Kinesiology, James Madison University, Harrisonburg, Virginia, VA 22807, USA. kurtisp@jmu.edu.ORCID 0000-0003-4803-9054
Sam R EmersonDepartment of Nutritional Sciences, Oklahoma State University, Stillwater, OK 74078, USA. sam.emerson@okstate.edu.ORCID 0000-0001-7439-0871
Oklahoma State University · USJames Madison University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA large post-meal triglyceride (TG) response is an independent risk factor for cardiovascular disease, but postprandial lipemia assessments are not clinically practical in their current form. Therefore, we assessed the validity of an abbreviated, clinically feasible protocol in measuring postprandial lipemia.

methodEighteen healthy adults (8 male and 10 female) completed 3 high-fat meal trials in random order: (1) a Standard in Lab (SL) protocol wherein blood draws (to determine TG) were made from a catheter at baseline and hourly for 6 h; (2) an Abbreviated in Lab (AL) protocol in which participants remained in the laboratory but blood draws were only made at baseline and 4 h post-meal; and (3) an Abbreviated with Freedom (AF) protocol in which participants vacated the laboratory between the meal and the 4-h blood draw.

resultsTG increase from baseline was very similar (

conclusionThe TG results of the clinically feasible, abbreviated protocol were similar to those of the more exhaustive standard protocol. The AF protocol could be a valid and feasible clinical tool for measurement of postprandial lipemia and assessment of cardiovascular risk, although studies in larger and more diverse cohorts are needed.

Indexed as

Postprandial PeriodAdolescentBlood GlucoseBody Mass IndexCholesterol, HDLCholesterol, LDLCross-Over StudiesDietary FatsDiet, High-FatFeasibility StudiesFemaleFollow-Up StudiesHumansHyperlipidemiasMaleMealsBlood GlucoseCholesterol, HDLCholesterol, LDLDietary FatsTriglyceridesfat tolerancepost-mealrisk assessmenttriglycerides

Identifiers

PMID30654471
PMCPMC6356282
OpenAlexW2910703073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.