Evidence map›Paper›PMID 30654363›Full record

SynthesisDigestive surgery2020

Long-Term Impact of Iatrogenic Bile Duct Injury.

Anne Marthe Schreuder, Olivier R Busch, Marc G Besselink, Povilas Ignatavicius, Antanas Gulbinas, Giedrius Barauskas, Dirk J Gouma, Thomas M van Gulik

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Digestive surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 6 pooled it
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 6 syntheses or guidelines pooled it, 149 citations in OpenAlex.

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  17. Review
  18. Bile Duct Injury and Litigation in Laparoscopic Cholecystectomy: A Global Review of Current and Future Preventative Initiatives.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2025
    Review
  19. Review
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Anne Marthe SchreuderDepartment of Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands, a.m.schreuder@amc.uva.nl.
Olivier R BuschDepartment of Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Marc G BesselinkDepartment of Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Povilas IgnataviciusDepartment of Surgery, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Antanas GulbinasDepartment of Surgery, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Giedrius BarauskasDepartment of Surgery, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Dirk J GoumaDepartment of Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Thomas M van GulikDepartment of Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Amsterdam University Medical Centers · NLLithuanian University of Health Sciences · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBile duct injury (BDI) is a devastating complication following cholecystectomy. After initial management of BDI, patients stay at risk for late complications including anastomotic strictures, recurrent cholangitis, and secondary biliary cirrhosis.

methodsWe provide a comprehensive overview of current literature on the long-term outcome of BDI. Considering the availability of only limited data regarding treatment of anastomotic strictures in literature, we also retrospectively analyzed patients with anastomotic strictures following a hepaticojejunostomy (HJ) from a prospectively maintained database of 836 BDI patients.

resultsAlthough clinical outcomes of endoscopic, radiologic, and surgical treatment of BDI are good with success rates of around 90%, quality of life (QoL) may be impaired even after "clinically successful" treatment. Following surgical treatment, the incidence of anastomotic strictures varies from 5 to 69%, with most studies reporting incidences around 10-20%. The median time to stricture formation varies between 11 and 30 months. Long-term BDI-related mortality varies between 1.8 and 4.6%. Of 91 patients treated in our center for anastomotic strictures after HJ, 81 (89%) were treated by percutaneous balloon dilatation, with a long-term success rate of 77%. Twenty-four patients primarily or secondarily underwent surgical revision, with recurrent strictures occurring in 21%.

conclusionsThe long-term impact of BDI is considerable, both in terms of clinical outcomes and QoL. Treatment should be performed in tertiary expert centers to optimize outcomes. Patients require a long-term follow-up to detect anastomotic strictures. Strictures should initially be managed by percutaneous dilatation, with surgical revision as a next step in treatment.

Indexed as

Iatrogenic DiseaseAnastomosis, Roux-en-YBile DuctsCholangitisCholecystectomyConstriction, PathologicDilatationHumansJejunumLiver Cirrhosis, BiliaryPrognosisQuality of LifeRecurrenceReoperationRetrospective StudiesAnastomotic strictureBile duct injuryBile leakageCholecystectomyLong-term outcome

Identifiers

PMID30654363
PMCPMC7026941
OpenAlexW2909722404

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.