Evidence map›Paper›PMID 30654232›Full record

ReviewCurrent opinion in cell biology2019

De novo formation and epigenetic maintenance of centromere chromatin.

Junichirou Ohzeki, Vladimir Larionov, William C Earnshaw, Hiroshi Masumoto

Open access · hybridAbstract readReview
In one paragraph

Review in Current opinion in cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. A unified photosensitizer platform forbioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. 40 years of CENP-A: the foundation of a new era of centromere biology.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Mitotic chromosomes.Seminars in cell & developmental biology · 2021
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Junichirou OhzekiLaboratory of Chromosome Engineering, Department of Frontier Research and Development, Kazusa DNA Research Institute, 2-6-7 Kazusa-Kamatari, Kisarazu 292-0818, Japan.
Vladimir LarionovGenome Structure and Function Group, Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
William C EarnshawWellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3BF, UK.
Hiroshi MasumotoLaboratory of Chromosome Engineering, Department of Frontier Research and Development, Kazusa DNA Research Institute, 2-6-7 Kazusa-Kamatari, Kisarazu 292-0818, Japan. Electronic address: masumoto@kazusa.or.jp.
Kazusa DNA Research Institute · JPNational Institutes of Health · USWellcome Centre for Cell Biology · GB

Funding

Study of hereditary prostate cancer and human artificial chromosomesZIABC010413 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LARIONOV, VLADIMIR · 2009 to 2025
$31.5M
Intramural NIH HHS ZIA BC010413Wellcome TrustWellcome Trust 073915
6 · The paper itself

Abstract

Accurate chromosome segregation is essential for cell proliferation. The centromere is a specialized chromosomal locus, on which the kinetochore structure is formed. The centromere/kinetochore is required for the equal separation of sister chromatids to daughter cells. Here, we review recent findings on centromere-specific chromatin, including its constitutive protein components, its de novo formation and maintenance mechanisms, and our progress in analyses with synthetic human artificial chromosomes (HACs).

Indexed as

AnimalsCentromereChromatinChromosomal Proteins, Non-HistoneChromosome SegregationEpigenesis, GeneticHeterochromatinHumansKinetochoresChromatinChromosomal Proteins, Non-HistoneHeterochromatin

Identifiers

PMID30654232
PMCPMC6626702
OpenAlexW2910666190

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.