ArticleThe journal of allergy and clinical immunology. In practice
Perceived Versus Actual Aeroallergen Sensitization in Urban Children.
Article in The journal of allergy and clinical immunology. In practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Inhalant-Specific IgE Profiles to Guide the Clinical Management and Prevention of Children with Respiratory Allergies in Fuzhou: A Cross-Sectional Cohort Study Based on ImmunoCAP.Journal of asthma and allergy · 2025Article
- Merged Affinity Network Association Clustering: Joint multi-omic/clinical clustering to identify disease endotypes.Cell reports · 2021Article
- Prevalence of food allergen and aeroallergen sensitization among children in Sichuan province.Medicine · 2020Observational
- Factors related to disagreement between self-reported versus objective measurement of allergen sensitization at a tertiary pediatric center in Beijing, China.BMC pediatrics · 2020Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundIndividuals often report allergy to specific aeroallergens, but allergy testing can reveal disparate sensitization.
objectiveTo characterize the agreement between perceived and actual sensitization to individual aeroallergens in an urban pediatric population.
methodsA total of 253 children were enrolled from pediatric clinics in New York, NY. Detailed questionnaires regarding perceived sensitization and serum specific IgE measurements to 10 common aeroallergens were completed. Agreement between perceived and actual sensitization (sIgE ≥ 0.35 kU
resultsA total of 161 (63.6%) of 253 children reported perceived sensitization to 1 or more aeroallergen, and 203 (80.2%) were actually sensitized to 1 or more aeroallergen. Agreement between perceived and actual aeroallergen sensitization was fair for most aeroallergens, with greatest agreement for cat dander (κ, 0.42; 95% CI, 0.32-0.53) and dust (κ, 0.32; 95% CI, 0.20-0.44). Models adjusted for potential confounders showed nearly 6-fold odds of sensitization to cat dander given perceived cat allergy (adjusted odds ratio, 5.82; 95% CI, 2.91-11.64), and over 2-fold odds of sensitization to Dermatophagoides pteronyssinus, Dermatophagoides farinae, dog dander, or grass pollen given perceived sensitization to their respective allergens. Among children with no perceived sensitization, actual sensitization ranged from 5.4% to 30.4%, and was more common for indoor versus outdoor allergens, including cockroach.
conclusionsChildren who perceive allergen sensitization to cat, dog, dust, or grass are likely to demonstrate actual sensitization to these individual allergens. Children with no perceived sensitization to allergens are nonetheless frequently sensitized.
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