Evidence map›Paper›PMID 30653796›Full record

Observational studyBJU international2019

Nomogram for predicting the likelihood of postoperative surgical complications in patients treated with partial nephrectomy: a prospective multicentre observational study (the RECORd 2 project).

Andrea Mari, Riccardo Campi, Riccardo Schiavina, Daniele Amparore, Alessandro Antonelli, Walter Artibani, Maurizio Barale, Roberto Bertini, Marco Borghesi, Pierluigi Bove and 21 more

Registry-linked trialOpen access · bronzeAbstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in BJU international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05363657 (International REgistry of COnservative or Radical Treatment of Localized Kidney Tumors), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05363657 recruitingnot on this mapstarted 2022, after this paper: background citation

International REgistry of COnservative or Radical Treatment of Localized Kidney Tumors (i-RECORd)

TypeobservationalSponsorAzienda Ospedaliero-Universitaria CareggiRan2022 to 2028Enrolled10,000ConditionsKidney CancerArmsPartial Nephrectomy (PN), Radical Nephrectomy (RN), Ablation therapy (AT), Active Surveillance (AS)
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

31 authors at 14 institutions in 1 country.

Andrea MariUnit of Oncologic Minimally-Invasive Urology and Andrology, Department of Urology, Careggi Hospital, University of Florence, Florence, Italy.ORCID 0000-0001-9070-5706
Riccardo CampiUnit of Oncologic Minimally-Invasive Urology and Andrology, Department of Urology, Careggi Hospital, University of Florence, Florence, Italy.ORCID 0000-0001-5237-0888
Riccardo SchiavinaDepartment of Urology, University of Bologna, Bologna, Italy.
Daniele AmparoreDivision of Urology, Department of Oncology, School of Medicine, San Luigi Gonzaga Hospital, Orbassano, Turin, Italy.
Alessandro AntonelliDepartment of Urology, Spedali Civili Hospital, University of Brescia, Brescia, Italy.
Walter ArtibaniDepartment of Urology, Azienda Ospedaliera Universitaria Integrata (A.O.U.I.), Verona, Italy.
Maurizio BaraleDivision of Urology, Department of Surgical Sciences, San Giovanni Battista Hospital, University of Studies of Torino, Turin, Italy.
Roberto BertiniUnit of Urology, Division of Experimental Oncology, URI-Urological Research Institute, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
Marco BorghesiDepartment of Urology, University of Bologna, Bologna, Italy.
Pierluigi BoveDepartment of Urology, University of Tor Vergata, San Carlo di Nancy Hospital, Rome, Italy.
Eugenio BrunocillaDepartment of Urology, University of Bologna, Bologna, Italy.
Umberto CapitanioUnit of Urology, Division of Experimental Oncology, URI-Urological Research Institute, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.ORCID 0000-0001-9225-1795
Luigi Da PozzoDepartment of Urology, Papa Giovanni XXIII Hospital, Bergamo, Italy.
Julian DajaDepartment of Urology, Spedali Civili Hospital, University of Brescia, Brescia, Italy.
Paolo GonteroDivision of Urology, Department of Surgical Sciences, San Giovanni Battista Hospital, University of Studies of Torino, Turin, Italy.
Alessandro LarcherUnit of Urology, Division of Experimental Oncology, URI-Urological Research Institute, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
Vincenzo Li MarziUnit of Urological Minimally Invasive Robotic Surgery and Renal Transplantation, Department of Urology, Careggi Hospital, University of Florence, Florence, Italy.
Nicola LongoDepartment of Urology, University Federico II of Naples, Naples, Italy.
Vincenzo MironeDepartment of Urology, University Federico II of Naples, Naples, Italy.
Emanuele MontanariDepartment of Urology, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
Francesca PisanoDivision of Urology, Department of Surgical Sciences, San Giovanni Battista Hospital, University of Studies of Torino, Turin, Italy.
Francesco PorpigliaDivision of Urology, Department of Oncology, School of Medicine, San Luigi Gonzaga Hospital, Orbassano, Turin, Italy.ORCID 0000-0001-8567-6795
Claudio SimeoneDepartment of Urology, Spedali Civili Hospital, University of Brescia, Brescia, Italy.
Salvatore SiracusanoDepartment of Urology, Azienda Ospedaliera Universitaria Integrata (A.O.U.I.), Verona, Italy.
Riccardo TelliniUnit of Oncologic Minimally-Invasive Urology and Andrology, Department of Urology, Careggi Hospital, University of Florence, Florence, Italy.
Carlo TrombettaU.C.O. Clinica Urologica, Università degli Studi di Trieste, Trieste, Italy.
Alessandro VolpeDepartment of Urology, Maggiore della Carità Hospital, Novara, Italy.
Vincenzo FicarraUrologic Section, Department of Human and Paediatric Pathology, University of Messina, Messina, Italy.
Marco CariniUnit of Oncologic Minimally-Invasive Urology and Andrology, Department of Urology, Careggi Hospital, University of Florence, Florence, Italy.
Andrea MinerviniUnit of Oncologic Minimally-Invasive Urology and Andrology, Department of Urology, Careggi Hospital, University of Florence, Florence, Italy.ORCID 0000-0001-5140-4628
Collaborators
Azienda Ospedaliero-Universitaria Careggi · ITAzienda Ospedaliero Universitaria San Giovanni Battista · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITUniversity of Bologna · ITVita-Salute San Raffaele University · ITAzienda Ospedaliera Universitaria Integrata Verona · ITFederico II University Hospital · ITOspedale San Luigi Gonzaga · ITAzienda Ospedaliera Ospedale Maggiore · ITOspedale Papa Giovanni XXIII · ITUniversity of Messina · ITUniversity of Milan · ITUniversity of Rome Tor Vergata · ITUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify meaningful predictors and to develop a nomogram of postoperative surgical complications in patients treated with partial nephrectomy (PN). PATIENTS AND

methodsWe prospectively evaluated 4308 consecutive patients who had surgical treatment for renal tumours, between 2013 and 2016, at 26 Italian urological centres (RECORd 2 project). A multivariable logistic regression for surgical complications was performed. A nomogram was created from the multivariable model. Internal validation processes were performed using bootstrapping with 1000 repetitions.

resultsOverall, 2584 patients who underwent PN were evaluated for the final analyses. The median (interquartile [IQR]) American Society of Anesthesiologists (ASA) score was 2 (2-3). In all, 72.4% of patients had clinical T1a (cT1a) stage tumours. The median (IQR) Preoperative Aspects and Dimensions Used for an Anatomical (PADUA) score was 7 (6-8). Overall, 34.3%, 27.7%, 38% of patients underwent open PN (OPN), laparoscopic PN (LPN), and robot-assisted PN (RAPN). Overall and major postoperative surgical complications were recorded in 10.2% and 2.5% of patients, respectively. At multivariable analysis, age, ASA score, cT2 vs cT1a stage, PADUA score, preoperative anaemia, OPN and LPN vs RAPN, were significant predictive factors of postoperative surgical complications. We used these variables to construct a nomogram for predicting the risk of postoperative surgical complications. At decision curve analysis, the nomogram led to superior outcomes for any decision associated with a threshold probability of >5%.

conclusionSeveral clinical predictors have been associated with postoperative surgical complications after PN. We used this information to develop and internally validate a nomogram to predict such risk.

Indexed as

AgedFemaleHumansKidney NeoplasmsMaleMiddle AgedNephrectomyNomogramsPostoperative ComplicationsProspective Studiescomplicationsnephron-sparing surgerynomogrampartial nephrectomyrenal cell carcinomarobot-assisted partial nephrectomy

Identifiers

PMID30653796
OpenAlexW2910821679

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Registered trials

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