ArticlePLoS neglected tropical diseases2019
Epidemiology of Strongyloides stercoralis infection in Bolivian patients at high risk of complications.
Article in PLoS neglected tropical diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence and Associated Risk Factors of Human Intestinal Helminths Parasitic Infections in Ethiopia: A Systematic Review and Meta-Analysis.TheScientificWorldJournal · 2022Pooled it
- Strongyloidiasis in Africa: Systematic Review and Meta-Analysis on Prevalence, Diagnostic Methods, and Study Settings.BioMed research international · 2020Pooled it
- Evaluation of strongyloidiasis prevalence in immunocompromised patients referred to hospitals: a case study of Iran's capital.BMC infectious diseases · 2025Article
- Detection of human strongyloidiasis among patients with a high risk of complications attending selected tertiary care hospitals in Colombo, Sri Lanka using molecular and serological diagnostic tools.Parasites & vectors · 2024Article
- Prevalence of Strongyloides stercoralis and other helminths in four districts of Madagascar.Tropical medicine and health · 2024Article
- The Seroepidemiology ofJournal of tropical medicine · 2024Article
- Strongyloides and COVID-19: Challenges and Opportunities for Future Research.Tropical medicine and infectious disease · 2023Review
- Prevalence and risk factors of Strongyloides stercoralis in haemodialysis in Cochabamba, Bolivia: a cross-sectional study.BMC nephrology · 2023Article
- A simple parasitological technique to increase detection of Strongyloides stercoralis in Bolivian primary health care system.BMC primary care · 2022Article
- Review
- Prevalence of Strongyloides stercoralis infection and associated clinical symptoms among schoolchildren living in different altitudes of Amhara National Regional State, northwest Ethiopia.PLoS neglected tropical diseases · 2022Article
- A Practical Approach to Screening forTropical medicine and infectious disease · 2021Article
- Effects of infections on the pathogenesis of cancer.The Indian journal of medical research · 2021Review
- Performance evaluation of Baermann techniques: The quest for developing a microscopy reference standard for the diagnosis of Strongyloides stercoralis.PLoS neglected tropical diseases · 2021Article
- Seroprevalence of thePathogens (Basel, Switzerland) · 2020Article
- Article
- scFv against HSP60 ofDisease markers · 2020Article
- Article
- Strongyloides stercoralis infection in San Marino Republic: first epidemiological data from an observational study.Epidemiology and infection · 2019Observational
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12 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundStrongyloidiasis can be fatal in immunocompromised patients, but few epidemiological studies investigated the burden of this neglected tropical disease among these populations, particularly in low- and middle-income countries such as Bolivia. This study aimed to fill in this gap by estimating prevalence rate and risk factors associated with strongyloidiasis among patients at high risk of complications.
methodsA cross-sectional study was carried out in Santa Cruz (elevation 400 meters, tropical climate) and Cochabamba (elevation 2,500 meters, temperate climate), among patients with cancer, HIV infection and rheumatic or hematologic disease, using four coproparasitological techniques and one serological (ELISA) test.
resultsIn total, 1,151 patients participated in this study, including individuals who were HIV-positive (30%) or with rheumatic (29%), oncologic (32%) or hematologic (9%) diseases. The serological and coproparasitological prevalence was 23.0% (95% confidence interval [CI], 20.7-25.5; n = 265/1151) and 7.6% (95% CI, 6.2-9.3; n = 88/1151), respectively, with an estimated actual prevalence of 20.2% (95% CI, 17.9-22.5). Positive serology and positive coproparasitology were associated with younger age and lower education levels. There was no significant difference in prevalence between Cochabamba and Santa Cruz as defined by coproparasitology (6.4% vs. 8.9%; p = 0.11) or serology (24.0% vs. 22.0%; p = 0.4). Among 64 patients in Cochabamba who had never travelled to the tropical lowlands, 5 (7.8%) had a positive coproparasitology.
conclusionsStrongyloidiasis is widely prevalent in Bolivia among vulnerable patients at increased risk of life-threatening complications. Transmission of the parasite occurs both in tropical lowlands and temperate elevation (≥ 2,500 m). Control strategies to prevent transmission and complications of this serious parasitic disease should be urgently reinforced.
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