ArticleMMWR. Morbidity and mortality weekly report2019
Gastroschisis Trends and Ecologic Link to Opioid Prescription Rates - United States, 2006-2015.
Article in MMWR. Morbidity and mortality weekly report, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Prenatal Opioid Use Disorder and the Risk of Congenital Anomalies in Offspring: A Population-Based Study.Birth defects research · 2025Article
- Gastroschisis: diagnosis, prognosis and treatment options.Frontiers in pediatrics · 2025Review
- County-Level Atrazine Use and Gastroschisis.JAMA network open · 2024Article
- National population-based estimates for major birth defects, 2016-2020.Birth defects research · 2024Article
- Socioeconomic, Ethnocultural, Substance- and Cannabinoid-Related Epidemiology of Down Syndrome USA 1986-2016: Combined Geotemporospatial and Causal Inference Investigation.International journal of environmental research and public health · 2022Observational
- Article
- Gastroschisis with intestinal atresia leads to longer hospitalization and poor feeding outcomes.Journal of perinatology : official journal of the California Perinatal Association · 2022Article
- Article
- Epidemiology of birth defects in teenage pregnancies: Based on provincial surveillance system in eastern China.Frontiers in public health · 2022Observational
- Opioid use in pregnancy: An emerging health crisis.Obstetric medicine · 2021Review
- Regional variation in gastroschisis: a nationwide database review of demographics and outcomes.Pediatric surgery international · 2021Article
- Abdominal Wall Defects-Current Treatments.Children (Basel, Switzerland) · 2021Review
- Assessing the relationship between neonatal abstinence syndrome and birth defects in Delaware.Birth defects research · 2021Article
- Gastroschisis: A State-of-the-Art Review.Children (Basel, Switzerland) · 2020Review
- Trends in prevalence and spatiotemporal distribution of gastroschisis in Arkansas, 1998-2015.Birth defects research · 2020Article
- Maternal occupational exposure to solvents and gastroschisis in offspring - National Birth Defects Prevention Study 1997-2011.Occupational and environmental medicine · 2020Article
- Does overweight before pregnancy reduce the occurrence of gastroschisis?: the Japan Environment and Children's Study.BMC research notes · 2020Article
- National population-based estimates for major birth defects, 2010-2014.Birth defects research · 2019Article
- Population-based birth defects data in the United States, 2012-2016: A focus on abdominal wall defects.Birth defects research · 2019Article
- Review
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26 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Prevalence of gastroschisis, a serious birth defect of the abdominal wall resulting in some of the abdominal contents extending outside the body at birth, has been increasing worldwide (1,2). Gastroschisis requires surgical repair after birth and is associated with digestive and feeding complications during infancy, which can affect development. Recent data from 14 U.S. states indicated an increasing prevalence of gastroschisis from 1995 to 2012 (1). Young maternal age has been strongly associated with gastroschisis, but research suggests that risk factors such as smoking, genitourinary infections, and prescription opioid use also might be associated (3-5). Data from 20 population-based state surveillance programs were pooled and analyzed to assess age-specific gastroschisis prevalence during two 5-year periods, 2006-2010 and 2011-2015, and an ecologic approach was used to compare annual gastroschisis prevalence by annual opioid prescription rate categories. Gastroschisis prevalence increased only slightly (10%) from 2006-2010 to 2011-2015 (prevalence ratio = 1.1, 95% confidence interval [CI] = 1.0-1.1), with the highest prevalence among mothers aged <20 years. During 2006-2015, the prevalence of gastroschisis was 1.6 times higher in counties with high opioid prescription rates (5.1 per 10,000 live births; CI = 4.9-5.3) and 1.4 times higher where opioid prescription rates were medium (4.6 per 10,000 live births; CI = 4.4-4.8) compared with areas with low prescription rates (3.2 per 10,000 live births; CI = 3.1-3.4). Public health research is needed to understand factors contributing to the association between young maternal age and gastroschisis and assess the effect of prescription opioid use during pregnancy on this pregnancy outcome.
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