Evidence map›Paper›PMID 30653310›Full record

ArticleJournal of the American Chemical Society2019

A Click Chemistry Approach Reveals the Chromatin-Dependent Histone H3K36 Deacylase Nature of SIRT7.

Wesley Wei Wang, Maria Angulo-Ibanez, Jie Lyu, Yadagiri Kurra, Zhen Tong, Bo Wu, Ling Zhang, Vangmayee Sharma, Jennifer Zhou, Hening Lin and 4 more

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 64 citations in OpenAlex.

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  16. Polyglycerol-Amine Covered Nanosheets Target Cell-Free DNA to Attenuate Acute Kidney Injury.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  17. Article
  18. Review
  19. Investigating Physiopathological Roles for Sirtuins in a Mouse Model.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Wesley Wei WangDepartment of Chemistry , Texas A&M University , College Station , Texas 77843 , United States.
Maria Angulo-IbanezDepartment of Medicine , Stanford University School of Medicine , Stanford , California 94305 , United States.
Jie LyuDivision of Biostatistics, Dan L. Duncan Cancer Center , Baylor College of Medicine , Houston , Texas 77030 , United States.
Yadagiri KurraDepartment of Chemistry , Texas A&M University , College Station , Texas 77843 , United States.
Zhen TongHoward Hughes Medical Institute, Department of Chemistry and Chemical Biology , Cornell University , Ithaca , New York 14853 , United States.
Bo WuDepartment of Chemistry , Texas A&M University , College Station , Texas 77843 , United States.
Ling ZhangInstitute of Theoretical and Computational Chemistry, College of Chemistry and Molecular Engineering , Peking University , Beijing 100871 , China.
Vangmayee SharmaDepartment of Chemistry , Texas A&M University , College Station , Texas 77843 , United States.
Jennifer ZhouDepartment of Chemistry , Texas A&M University , College Station , Texas 77843 , United States.
Hening LinHoward Hughes Medical Institute, Department of Chemistry and Chemical Biology , Cornell University , Ithaca , New York 14853 , United States.ORCID 0000-0002-0255-2701
Yi Qin GaoInstitute of Theoretical and Computational Chemistry, College of Chemistry and Molecular Engineering , Peking University , Beijing 100871 , China.ORCID 0000-0002-4309-9376
Wei LiDivision of Biostatistics, Dan L. Duncan Cancer Center , Baylor College of Medicine , Houston , Texas 77030 , United States.
Katrin F ChuaDepartment of Medicine , Stanford University School of Medicine , Stanford , California 94305 , United States.
Wenshe Ray LiuDepartment of Chemistry , Texas A&M University , College Station , Texas 77843 , United States.ORCID 0000-0002-7078-6534
Texas A&M University · USBaylor College of Medicine · USHoward Hughes Medical Institute · USPeking University · CNStanford University · USVA Palo Alto Health Care System · US

Funding

Chemical Approaches for Studying the Biology of NAD-consuming EnzymesR01GM086703 · NIGMS · CORNELL UNIVERSITY · PI LIN, HENING · 2009 to 2017
$2.5M
Molecular Mechanisms of Mammalian SIRT6 FunctionR01AG050997 · NIA · PALO ALTO VETERANS INSTIT FOR RESEARCH · PI CHUA, KATRIN F · 2016 to 2020
$1.7M
Studying Reversible Histone Acylations in Nucleosome ContextsR01GM121584 · NIGMS · TEXAS A&M UNIVERSITY · PI LIU, WENSHE RAY · 2017 to 2020
$1.3M
Molecular Mechanisms of Mammalian SIRT6 FunctionR56AG050997 · NIA · PALO ALTO VETERANS INSTIT FOR RESEARCH · PI CHUA, KATRIN F · 2015 to 2015
$487k
Elucidating functions of mammalian SIRT7 deacetylase in aging and diseaseI01BX000286 · VA · VETERANS ADMIN PALO ALTO HEALTH CARE SYS · PI Katrin F. Chua · 2009 to 2026
–
BLRD VA I01 BX000286NIA NIH HHS R01 AG050997NIA NIH HHS R56 AG050997NIGMS NIH HHS R01 GM086703NIGMS NIH HHS R01 GM121584
6 · The paper itself

Abstract

Using an engineered pyrrolysyl-tRNA synthetase mutant together with tRNA

Indexed as

AcylationBiocatalysisCatalytic DomainChromatinClick ChemistryHistonesLysineModels, MolecularNucleosomesSirtuinsChromatinHistonesLysineNucleosomesSirtuins

Identifiers

PMID30653310
PMCPMC6812484
OpenAlexW2908901409

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.