ArticleeLife2019
Nostril-specific and structure-based olfactory learning of chiral discrimination in human adults.
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Article
- The behavioral sensitivity of mice to acyclic, monocyclic, and bicyclic monoterpenes.PloS one · 2024Article
- Bilateral and unilateral odor processing and odor perception.Communications biology · 2020Review
- Cell-Type-Specific Whole-Brain Direct Inputs to the Anterior and Posterior Piriform Cortex.Frontiers in neural circuits · 2020Article
- Is It Possible to Predict the Odor of a Molecule on the Basis of its Structure?International journal of molecular sciences · 2019Review
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Authors and funding
2 authors.
Funding
Abstract
Practice makes perfect. In human olfaction, such plasticity is generally assumed to occur at the level of cortical synthetic processing that shares information from both nostrils. Here we present findings that challenge this view. In two experiments, we trained human adults unirhinally for the discrimination between odor enantiomers over a course of about 10 to 11 days. Results showed that training-induced perceptual gain was restricted to the trained nostril yet partially generalized to untrained odor enantiomers in a structure- rather than quality- based manner. In other words, learning enhanced the differentiation of chirality (molecular configuration) as opposed to overall odor quality (odor object) per se. These findings argue that, unlike earlier beliefs, one nostril does not readily know what the other learns. Moreover, the initial analytical processing of the structural features of uninarial olfactory input remains plastic in human adults.
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Registered trials
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