Evidence map›Paper›PMID 30652364›Full record

ArticleEuropean journal of cancer care2019

Cost-of-illness of metastatic gastroenteropancreatic neuroendocrine tumours in Sweden-A population-based register-linkage study.

Eva Lesén, Daniel Granfeldt, Aude Houchard, Anthony Berthon, Jérôme Dinet, Sylvie Gabriel, Åse Björstad, Ingela Björholt, Anna-Karin Elf, Viktor Johanson

Open access · hybridAbstract read
In one paragraph

Article in European journal of cancer care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Use of healthcare REsources and associated COsts in controlled versus uncontrolled carcinoid SYndrome in patients with neuroendocrine tumours: the RECOSY study.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021
    Observational
  6. Review
  7. Cost-effectiveness of lutetium (World journal of clinical cases · 2020
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Eva LesénNordic Health Economics, Gothenburg, Sweden.
Daniel GranfeldtPharmaLex Sweden, formerly Nordic Health Economics, Gothenburg, Sweden.
Aude HouchardIpsen, Boulogne-Billancourt, France.
Anthony BerthonIpsen, Boulogne-Billancourt, France.
Jérôme DinetIpsen, Boulogne-Billancourt, France.
Sylvie GabrielIpsen, Boulogne-Billancourt, France.
Åse BjörstadPharmaLex Sweden, formerly Nordic Health Economics, Gothenburg, Sweden.
Ingela BjörholtPharmaLex Sweden, formerly Nordic Health Economics, Gothenburg, Sweden.
Anna-Karin ElfDepartment of Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden.
Viktor JohansonDepartment of Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden.
Ipsen (France) · FRNordic School of Public Health · SESahlgrenska University Hospital · SE

Funding

Ipsen
6 · The paper itself

Abstract

The objective was to estimate the cost-of-illness of grades 1 and 2 metastatic gastroenteropancreatic neuroendocrine tumours (GEP-NETs) in Sweden in 2013 in a population-based study including all patients diagnosed between 2005 and 2013. Data were obtained from national registers, and patients who utilised healthcare resources due to metastatic GEP-NETs in 2013 were included. The study included 478 patients (mean age 64 [SD=11] years, 51% men). The majority (80%) had small intestinal NET, 10% had pancreatic NET, and 41% had carcinoid syndrome. The total cost-of-illness was €12,189,000 in 2013, of which direct costs constituted 77% and costs from production loss constituted 22%. The largest contributor to the direct medical costs was prescription drugs (54%; primarily somatostatin analogues [91% of the total drug cost]). Production loss due to sickness absence constituted 52% of the total costs of production loss. The total annual cost per patient was €25,500. By patient group, the cost was €24,800 (95% CI €21,600-€28,100) for patients with small intestinal NET, €37,300 (95% CI €23,300-€51,300) for those with pancreatic NET and €18,600 (95% CI €12,600-€24,500) for patients with other GEP-NETs. To conclude, the total annual cost of grades 1 and 2 metastatic GEP-NETs in Sweden was €25,500 per patient and year.

Indexed as

Cost of IllnessFemaleHealth Care CostsHealth ExpendituresHumansIntestinal NeoplasmsMaleMalignant Carcinoid SyndromeMiddle AgedNeoplasm MetastasisNeuroendocrine TumorsPancreatic NeoplasmsPatient Acceptance of Health CareRegistriesStomach NeoplasmsSwedencost-of-illnessGEP-NETmetastaticregister studySwedentreatment

Identifiers

PMID30652364
PMCPMC9285913
OpenAlexW2911179395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.