ArticleJournal of general internal medicine2019
Spatial Clusters of Breast Cancer Mortality and Incidence in the Contiguous USA: 2000-2014.
Article in Journal of general internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Effects of Post-diagnosis Recreational Aerobic Exercise among Breast Cancer Survivors: A Systematic Review/Meta-Analysis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025Pooled it
- Area-Level Determinants in Colorectal Cancer Spatial Clustering Studies: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Geospatial heterogeneity of hotspots for incidence and late-stage diagnosis of breast, colorectal, and lung cancer.Cancer causes & control : CCC · 2026Article
- Spatial and temporal modeling of breast cancer mortality in Kansas: An R-INLA approach.PloS one · 2026Article
- Geospatial disparities, health system factors, and breast cancer care quality.JNCI cancer spectrum · 2025Article
- Where Should the Cancer Control Interventions Target: A Geospatial Hotspot Analysis for Major Cancer Mortality 2018 to 2022 in the United States.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025Article
- Geospatial Analysis of Breast Cancer Incidence, Mortality, and Access to Screening in Rural and Appalachian Virginia.Journal of Appalachian health · 2025Article
- ClusterRadar: An interactive web-tool for the multi-method exploration of spatial clusters over time.PloS one · 2025Article
- Trends in breast cancer mortality in Mexican women.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025Article
- Critical Risk Assessment, Diagnosis, and Survival Analysis of Breast Cancer.Diagnostics (Basel, Switzerland) · 2024Article
- Article
- Changes in spatial clusters of cancer incidence and mortality over 15 years in South Korea: Implication to cancer control.Cancer medicine · 2023Article
- Temporal Trends in the Incidence and Mortality of Major Reproductive-Related Cancers in Women in Guangzhou From 2010 to 2020: A Joinpoint and Age-Period-Cohort Study.International journal of public health · 2023Article
- Mortality trends of breast and cervical cancer in Passo Fundo, Rio Grande do Sul: an analysis by age and schooling, 1999-2019.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2023Article
- Intra-urban spatial variability of breast and cervical cancer mortality in the city of São Paulo: analysis of associated factors.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2023Article
- Comparing spatial patterns of 11 common cancers in Mainland China.BMC public health · 2022Article
- Government drivers of breast cancer prevention: A spatiotemporal analysis based on the association between breast cancer and macro factors.Frontiers in public health · 2022Article
- Mapping of Female Breast Cancer Incidence and Mortality Rates to Socioeconomic Factors Cohort: Path Diagram Analysis.Frontiers in public health · 2021Observational
- Article
- Spatial pattern of mortality from breast and cervical cancer in the city of São Paulo.Revista de saude publica · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundClusters of breast cancer with varied incidence or mortality are known to exist. No national scale of analysis of geographical variation in breast cancer incidence has been published before for the contiguous USA.
methodsThis was a spatial cluster analysis of incidence and mortality data on breast cancer in the contiguous USA at the county resolution. Data for the years 2000-2014 were downloaded and analyzed with the software SaTScan with the goal to identify significant spatial clusters of breast cancer. Regression analysis was used to then adjust breast cancer incidence and mortality for several key risk factors such as age, smoking, particulate matter air pollution, physical inactivity, urban living, education level, and race.
resultsSpatial clusters of counties for higher than expected breast cancer incidence and also for breast cancer mortality were identified. All identified clusters have p < 0.05. The mortality clusters show the mean breast cancer rates inside the cluster, while the incidence clusters show the relative risk inside each cluster. This is the first study of the contiguous USA for breast cancer mortality and incidence together. The clustering for mortality is quite different from the clustering for incidence. Using the software JOINPOINT, it is shown that the annual US downward trend for breast cancer mortality slowed down in recent years.
conclusionsThere exist several significant clusters in the contiguous USA, both for breast cancer incidence and for breast cancer mortality. Some of the clusters persisted even after adjusting for several key risk factors. These geographic areas warrant further investigation to potentially identify additional local concerns or needs to further address female breast cancer in those specific sites.
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