Evidence map›Paper›PMID 30652221›Full record

ArticleInternational orthopaedics2019

Functional outcome of two-stage reimplantation in patients with periprosthetic joint infection after primary total knee arthroplasty.

Petr Mikhailovich Preobrazhensky, Svetlana Anatolievna Bozhkova, Alexander Viktorovich Kazemirsky, Rashid Murtazalievich Tikhilov, Taras Andreevich Kulaba, Nikolai Nikolaevich Kornilov

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Article in International orthopaedics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
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  11. Customized intraoperatively molded articulating cement spacers for two-stage revisions TKA with major bone defects.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2021
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  15. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Petr Mikhailovich PreobrazhenskyRussian Scientific Research Institute of Traumatology and Orthopedics named after R.R. Vreden, Akademika Baykova St., 8, St. Petersburg, 195427, Russian Federation. p.preobrazhensky@gmail.com.ORCID 0000-0002-9569-1566
Svetlana Anatolievna BozhkovaRussian Scientific Research Institute of Traumatology and Orthopedics named after R.R. Vreden, Akademika Baykova St., 8, St. Petersburg, 195427, Russian Federation.
Alexander Viktorovich KazemirskyRussian Scientific Research Institute of Traumatology and Orthopedics named after R.R. Vreden, Akademika Baykova St., 8, St. Petersburg, 195427, Russian Federation.
Rashid Murtazalievich TikhilovRussian Scientific Research Institute of Traumatology and Orthopedics named after R.R. Vreden, Akademika Baykova St., 8, St. Petersburg, 195427, Russian Federation.
Taras Andreevich KulabaRussian Scientific Research Institute of Traumatology and Orthopedics named after R.R. Vreden, Akademika Baykova St., 8, St. Petersburg, 195427, Russian Federation.
Nikolai Nikolaevich KornilovRussian Scientific Research Institute of Traumatology and Orthopedics named after R.R. Vreden, Akademika Baykova St., 8, St. Petersburg, 195427, Russian Federation.
Russian Scientific Research Institute of Traumatology and Orthopedics named after R.R. Vreden · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTwo-stage reimplantation in patients with chronic periprosthetic joint infection (PJI) after total knee arthroplasty (TKA) with the use of either articulating or static antibiotic-loaded spacers during the first step is considered to be the golden standard in orthopaedics. THE AIM OF THE STUDY: The aim of the study was to evaluate the correlation of spacer type with the infection elimination rate as well as functional outcomes after two-staged revision TKA in patients with PJI. MATERIALS AND

methodsThe cohort comprised 161 patients who were treated for PJI after TKA during a period from January 2007 to December 2015. After the exclusion of patients with severe bone defects (AORI 2B or 3), 104 were left for the analysis: 72 patients with articulating and 32 with static spacers. The overall patient mean age was 62 years old (95% CI, 30-84): 73 for females, 31 for males. The outcomes were evaluated after three, six and 12 months using the American Knee Society Score (KSS) and EQ-5D. Only 92 patients were available for observation: 25 with static and 67 with articulating spacers.

resultsOne year after the surgery, patients with articulating spacers demonstrated significantly higher mean KSS and function scores in comparison to patients with static spacers (90.4, 77.3 and 78.5, 67.8, respectively (p < 0.05)). The range of motion was also significantly better in patients with articulating spacers: 104.9° in comparison to 93.9° (р < 0.0001). The final EQ-5D score was comparable in both groups (0.82, 73.1 in articulating and 0.82, 72.6 in static spacers).

conclusionThe two-stage revision TKA for PJI using articulating spacers in comparison to the static ones provides better infection eradication rate as well as functional outcomes and improved quality of life.

Indexed as

Arthroplasty, Replacement, KneeReplantationAdultAgedAged, 80 and overArthritis, InfectiousFemaleHumansKnee JointMaleMiddle AgedProsthesis-Related InfectionsQuality of LifeRange of Motion, ArticularTreatment OutcomeOutcomePeriprosthetic joint infectionQuality of lifeSpacerTotal knee arthroplastyTwo-stage revision

Identifiers

PMID30652221
OpenAlexW2910255234

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.