ArticleWorld journal of urology2019
A multicentric study on accurate grading of prostate cancer with systematic and MRI/US fusion targeted biopsies: comparison with final histopathology after radical prostatectomy.
Article in World journal of urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- [Influence of MRI fusion biopsy on treatment recommendations : How reliable are biopsy results?]Urologie (Heidelberg, Germany) · 2026Article
- Gleason Regrading After Prostatectomy-Results From the Irish Prostate Cancer Outcome Research (IPCOR) Situated in the International Context.International journal of urology : official journal of the Japanese Urological Association · 2026Article
- Transperineal cognitive fusion MRI-targeted biopsy shows higher detection rates than systematic biopsy in prostate cancer: a prospective cohort study.BMC urology · 2025Article
- [A preoperative prediction model for pelvic lymph node metastasis in prostate cancer: Integrating clinical characteristics and multiparametric MRI].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025Article
- Diagnostic Superiority of Transperineal Combined Fusion Biopsy Versus Transrectal Ultrasound-Guided Biopsy: Lower Upgrading Rates and Better Concordance with Post-Surgical Histopathology.Journal of clinical medicine · 2025Article
- The impact of biopsy core length on the discrepancy in Gleason scores between biopsy and radical prostatectomy specimen.BJUI compass · 2025Article
- Value of a confirmatory re-biopsy as part of a modern risk stratified cancer surveillance programme for early prostate cancer.BJUI compass · 2024Article
- Histopathological concordance between prostate biopsies and radical prostatectomy specimens-implications of transrectal and transperineal biopsy approaches.Prostate cancer and prostatic diseases · 2024Article
- The impact of mpMRI-targeted vs systematic biopsy on the risk of prostate cancer downgrading at final pathology.World journal of urology · 2024Article
- Cognitive fusion-targeted biopsy versus transrectal ultrasonography-guided systematic biopsy: comparison and analysis of the risk of Gleason score upgrading.International urology and nephrology · 2024Article
- The feasibility of MR elastography with transpelvic vibration for localization of focal prostate lesion.Scientific reports · 2024Article
- The number of involved regions by prostate adenocarcinoma predicts histopathology concordance between radical prostatectomy specimens and MRI/ultrasound-fusion targeted prostate biopsy.Frontiers in oncology · 2024Article
- Comparing histology between prostate cognitive fusion targeted biopsy and radical prostatectomy: exploring risk factors of Gleason score upgrading in Chinese patients.Journal of cancer research and clinical oncology · 2023Article
- MRI-targeted biopsy cores from prostate index lesions: assessment and prediction of the number needed.Prostate cancer and prostatic diseases · 2023Article
- Adverse Pathology after Radical Prostatectomy of Patients Eligible for Active Surveillance-A Summary 7 Years after Introducing mpMRI-Guided Biopsy in a Real-World Setting.Bioengineering (Basel, Switzerland) · 2023Article
- The prognostic value ofFrontiers in oncology · 2023Article
- Suitability of conventional systematic vs. MRI-guided targeted biopsy approaches to assess surgical treatment delay for radical prostatectomy.World journal of urology · 2022Article
- Article
- Cancer-specific outcomes for prostate cancer patients who had prebiopsy prostate MRI.Urologic oncology · 2022Article
- Selective Bone Scan staging for patients with Prostate cancer: do absolute categories really make sense?Prostate cancer and prostatic diseases · 2022Article
Corrections and comments
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Authors and funding
26 authors.
Funding
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Abstract
objectiveTo evaluate the accuracy in histologic grading of MRI/US image fusion biopsy by comparing histopathology between systematic biopsies (SB), targeted biopsies (TB) and the combination of both (SB + TB) with the final histopathologic outcomes of radical prostatectomy specimens. MATERIALS AND
methodsRetrospective, multicentric study of 443 patients who underwent SB and TB using MRI/US fusion technique (Urostation
resultsConcordance in ISUP (International Society of Urological Pathology) grade between SB, TB and SB + TB with final histopathology was 49.4%, 51.2%, and 63.2% for overall prostate cancer and 41.2%, 48.3%, and 56.7% for significant prostate cancer (ISUP grade ≥ 2), respectively. Significant difference in terms of concordance, downgrading and upgrading was found between SB and TB (ISUP grade ≥ 2 only), SB and SB + TB, TB and SB + TB (overall ISUP grade and ISUP grade ≥ 2) (p < 0.001). Total number of cores and previous biopsies were significant independent predictive factors for concordance with TB technique.
conclusionIn this retrospective study, combination of SB and TB significantly increased concordance with final histopathology despite a limited additional number of cores needed.
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