Evidence map›Paper›PMID 30652129›Full record

ArticleCommunications biology2019

Genetically encoded fluorescent indicators for imaging intracellular potassium ion concentration.

Yi Shen, Sheng-Yi Wu, Vladimir Rancic, Abhi Aggarwal, Yong Qian, Shin-Ichiro Miyashita, Klaus Ballanyi, Robert E Campbell, Min Dong

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 152 citations in OpenAlex.

  1. Article
  2. Slowing Down Water: Enhanced and Cation-responsive MRI Contrast.Angewandte Chemie (International ed. in English) · 2026
    Article
  3. Localizable Fluorescent Metal Ion Indicators With Tunable Colors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. A Historical Outline of Fluorescence Spectroscopy in Ion Channel Research.Advances in experimental medicine and biology · 2026
    Review
  10. CRISPR/Cas9-mediatedFrontiers in physiology · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Yi Shen1Department of Urology, Boston Children's Hospital, Department of Microbiology and Immunobiology, Department of Surgery, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115 USA.ORCID 0000-0003-4117-0279
Sheng-Yi Wu2Department of Chemistry, University of Alberta, Edmonton, AB T6G 2G2 Canada.
Vladimir Rancic3Department of Physiology, University of Alberta, Edmonton, AB T6G 2H7 Canada.
Abhi Aggarwal2Department of Chemistry, University of Alberta, Edmonton, AB T6G 2G2 Canada.
Yong Qian2Department of Chemistry, University of Alberta, Edmonton, AB T6G 2G2 Canada.
Shin-Ichiro Miyashita1Department of Urology, Boston Children's Hospital, Department of Microbiology and Immunobiology, Department of Surgery, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115 USA.
Klaus Ballanyi3Department of Physiology, University of Alberta, Edmonton, AB T6G 2H7 Canada.
Robert E Campbell2Department of Chemistry, University of Alberta, Edmonton, AB T6G 2G2 Canada.
Min Dong1Department of Urology, Boston Children's Hospital, Department of Microbiology and Immunobiology, Department of Surgery, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115 USA.
University of Alberta · CABoston Children's Hospital · US

Funding

STRUCTURE-FUNCTION RELATIONSHIPS IN THE ALIMENTARY TRACTP30DK034854 · NIDDK · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WAYNE I LENCER · 1986 to 2026
$32.4M
Structure and Function of C. Difficile ToxinsR01AI139087 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI Min Dong, Rongsheng Jin · 2018 to 2026
$7.4M
Long-term effects of botulinum neurotoxins on neuronal viabilityR01NS080833 · NINDS · HARVARD MEDICAL SCHOOL · PI Min Dong · 2013 to 2026
$6.8M
Molecular basis of action and pathogenesis of Clostridium difficile toxin BR01AI132387 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI DONG, MIN · 2017 to 2021
$3.5M
Northern Lights collaboration for better 2-photon probesU01NS094246 · NINDS · MONTANA STATE UNIVERSITY - BOZEMAN · PI CAMPBELL, ROBERT E., DROBIZHEV, MIKHAIL · 2015 to 2017
$2.0M
Development of Protein-based Voltage ProbesU01NS090565 · NINDS · JOHN B. PIERCE LABORATORY, INC. · PI PIERIBONE, VINCENT A · 2014 to 2016
$1.7M
Molecular mechanism for retrograde transport of tetanus neurotoxinR21NS106159 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI DONG, MIN · 2018 to 2019
$487k
CIHR FS 154310NIAID NIH HHS R01 AI132387NIAID NIH HHS R01 AI139087NIDDK NIH HHS P30 DK034854NINDS NIH HHS R01 NS080833NINDS NIH HHS R21 NS106159NINDS NIH HHS U01 NS090565NINDS NIH HHS U01 NS094246
6 · The paper itself

Abstract

Potassium ion (K

Indexed as

CalciumCarrier ProteinsCations, MonovalentCytosolEscherichia coliEscherichia coli ProteinsFluorescence Resonance Energy TransferFluorescent DyesGreen Fluorescent ProteinsHeLa CellsHumansIonsLuminescent ProteinsMicroscopy, FluorescenceOsmolar ConcentrationPlasmidsCalciumCarrier ProteinsCations, Monovalentenhanced green fluorescent proteinEscherichia coli ProteinsFluorescent DyesGreen Fluorescent ProteinsIonsLuminescent ProteinsPotassiumRed Fluorescent Protein

Identifiers

PMID30652129
PMCPMC6331434
OpenAlexW2911437499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.