Evidence map›Paper›PMID 30652082›Full record

ArticleFEBS open bio2019

The potential roles of long non-coding RNAs in lipopolysaccharide-induced human peripheral blood mononuclear cells as determined by microarray analysis.

Anqiang Zhang, Hongxiang Lu, Dalin Wen, Jianhui Sun, Juan Du, Xu Wang, Wei Gu, Jianxin Jiang

Open access · goldAbstract read
In one paragraph

Article in FEBS open bio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Long Noncoding RNA: Regulatory Mechanisms and Therapeutic Potential in Sepsis.Frontiers in cellular and infection microbiology · 2021
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Anqiang ZhangState Key Laboratory of Trauma, Burns and Combined Injury Institute of Surgery Research Daping Hospital Army Medical University Chongqing China.
Hongxiang LuState Key Laboratory of Trauma, Burns and Combined Injury Institute of Surgery Research Daping Hospital Army Medical University Chongqing China.
Dalin WenState Key Laboratory of Trauma, Burns and Combined Injury Institute of Surgery Research Daping Hospital Army Medical University Chongqing China.
Jianhui SunState Key Laboratory of Trauma, Burns and Combined Injury Institute of Surgery Research Daping Hospital Army Medical University Chongqing China.
Juan DuState Key Laboratory of Trauma, Burns and Combined Injury Institute of Surgery Research Daping Hospital Army Medical University Chongqing China.
Xu WangState Key Laboratory of Trauma, Burns and Combined Injury Institute of Surgery Research Daping Hospital Army Medical University Chongqing China.
Wei GuState Key Laboratory of Trauma, Burns and Combined Injury Institute of Surgery Research Daping Hospital Army Medical University Chongqing China.
Jianxin JiangState Key Laboratory of Trauma, Burns and Combined Injury Institute of Surgery Research Daping Hospital Army Medical University Chongqing China.
Army Medical University · CNDaping Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis arises from an aberrant and excessive host response to infection. Long noncoding RNAs (lncRNAs) are involved in multiple cellular functions, including inflammation and immunity. However, to date there has been no systematic attempt to identify lncRNAs whose expression is changed after the induction of the innate immune response. In this study, we profiled global lncRNA and mRNA expression changes in peripheral blood mononuclear cells (PBMCs) treated with lipopolysaccharide (LPS) using a microarray platform. Of the 40 914 lncRNAs screened, 596 were significantly upregulated and 250 were significantly downregulated (corrected

Indexed as

Gene Expression ProfilingHumansLeukocytes, MononuclearLipopolysaccharidesRNA, Long NoncodingRNA, MessengerSequence Analysis, RNALipopolysaccharidesRNA, Long NoncodingRNA, MessengerinflammationlipopolysaccharidelncRNAmicroarrayperipheral blood mononuclear cell

Identifiers

PMID30652082
PMCPMC6325599
OpenAlexW2903722671

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.