Evidence map›Paper›PMID 30652051›Full record

ArticleJournal of pharmacopuncture2018

The Preventive Effects of Standardized Extract of

Reza Mohebbati, Maryam Paseban, Farimah Beheshti, Mohammad Soukhtanloo, Mohammad Naser Shafei, Hasan Rakhshandeh, Abolfazl Khajavi Rad

Open access · diamondAbstract read
In one paragraph

Article in Journal of pharmacopuncture, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Food science & nutrition · 2024
    Article
  2. Article
  3. Review
  4. Article
  5. Avicenna journal of phytomedicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Reza MohebbatiDepartment of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Maryam PasebanDepartment of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Farimah BeheshtiDepartment of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad SoukhtanlooDepartment of Clinical Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad Naser ShafeiNeurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Hasan RakhshandehPharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Mashhad, Iran.
Abolfazl Khajavi RadDepartment of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mashhad University of Medical Sciences · IRCzech Academy of Sciences, Institute of Physiology · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe hepatotoxicity induced by Acetaminophen (AAP) mostly mediated by effect on oxidative stress parameters. The

methodsRats were randomly divided into four groups including: 1) Control, 2) Acetaminophen (AAP), 3) and 4) CAR. The saline, Z.M (200 mg/kg) and CAR (20 mg/kg) were administrated orally for 6 days, after that AAP (600 mg/kg) was administrated in the 7

resultsThe Δ GOT, Δ GPT and Δ ALP in CAR group significantly decreased compared to AAP group (P < 0.01 to P < 0.001) and Δ GPT in Z.M group was significantly reduced in comparison with AAP group (P < 0.05). Also, MDA, Thiol, SOD and CAT levels in treated groups were attenuated compared to AAP group (P < 0.05 to P < 0.001).

conclusionZ.M and CAR have a powerful hepatoprotective effect. CAR is more effective than Z.M. Based on the results. Z.M and CAR could be potent supplementary agents against hepatotoxicity of AAP in patients.

Indexed as

acetaminophencarvacrolhepatotoxicityZataria multiflora

Identifiers

PMID30652051
PMCPMC6333197
OpenAlexW2908071606

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.