Evidence map›Paper›PMID 30651982›Full record

ArticleLight, science & applications2019

Spectral contrast optical coherence tomography angiography enables single-scan vessel imaging.

James A Winkelmann, Aya Eid, Graham Spicer, Luay M Almassalha, The-Quyen Nguyen, Vadim Backman

Abstract read
In one paragraph

Article in Light, science & applications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Relevance of Microvascular Flow Assessments in Critically Ill Neonates and Children: A Systematic Review.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2020
    Pooled it
  3. Article
  4. Review
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  6. aXonica: A support package for MRI based Neuroimaging.Biotechnology notes (Amsterdam, Netherlands) · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

James A Winkelmann1Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208 USA.
Aya Eid1Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208 USA.
Graham Spicer2Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL 60208 USA.
Luay M Almassalha1Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208 USA.
The-Quyen Nguyen1Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208 USA.
Vadim Backman1Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208 USA.

Funding

An in vivo metastasis sensorR01CA173745 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BACKMAN, VADIM, SHEA, LONNIE D · 2012 to 2016
$4.2M
Biophotonics to Couple Pancreatic with Upper GI Screening via Ultrathin EndoscopyR01CA183101 · NCI · NORTHWESTERN UNIVERSITY · PI BACKMAN, VADIM, ROGERS, JEREMY D. · 2015 to 2019
$3.2M
Risk-stratification of Prostate Cancers via Field Carcinogenesis NanocytologyR01CA200064 · NCI · NORTHWESTERN UNIVERSITY · PI BACKMAN, VADIM, CRAWFORD, SUSAN E. · 2015 to 2019
$3.1M
Nanoscale/Molecular analysis of Fecal Colonocytes for Colorectal Cancer ScreeningR01CA165309 · NCI · NORTHWESTERN UNIVERSITY · PI BACKMAN, VADIM, ROY, HEMANT K. · 2012 to 2016
$2.8M
NCI NIH HHS R01 CA165309NCI NIH HHS R01 CA173745NCI NIH HHS R01 CA183101NCI NIH HHS R01 CA200064
6 · The paper itself

Abstract

Optical coherence tomography angiography relies on motion for contrast and requires at least two data acquisitions per pointwise scanning location. We present a method termed spectral contrast optical coherence tomography angiography using visible light that relies on the spectral signatures of blood for angiography from a single scan using endogenous contrast. We demonstrate the molecular sensitivity of this method, which enables lymphatic vessel, blood, and tissue discrimination.

Identifiers

PMID30651982
PMCPMC6333625

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.