Evidence map›Paper›PMID 30651970›Full record

ArticleCell & bioscience2019

Transmembrane protein 108 involves in adult neurogenesis in the hippocampal dentate gyrus.

Zheng Yu, Dong Lin, Yanzi Zhong, Bin Luo, Shengsheng Liu, Erkang Fei, Xinsheng Lai, Suqi Zou, Shunqi Wang

Open access · goldAbstract read
In one paragraph

Article in Cell & bioscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
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  5. Rebound activation of 5-HT neurons following SSRI discontinuation.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
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  9. Review
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  17. Review
  18. The Candidate Schizophrenia Risk GeneFrontiers in endocrinology · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Zheng Yu *1Laboratory of Synaptic Development and Plasticity, Institute of Life Science and School of Life Sciences, Nanchang University, Nanchang, Jiangxi China.
Dong Lin *1Laboratory of Synaptic Development and Plasticity, Institute of Life Science and School of Life Sciences, Nanchang University, Nanchang, Jiangxi China.
Yanzi Zhong1Laboratory of Synaptic Development and Plasticity, Institute of Life Science and School of Life Sciences, Nanchang University, Nanchang, Jiangxi China.
Bin Luo1Laboratory of Synaptic Development and Plasticity, Institute of Life Science and School of Life Sciences, Nanchang University, Nanchang, Jiangxi China.
Shengsheng Liu3Queen Mary School, Nanchang University, Nanchang, Jiangxi China.
Erkang Fei1Laboratory of Synaptic Development and Plasticity, Institute of Life Science and School of Life Sciences, Nanchang University, Nanchang, Jiangxi China.
Xinsheng Lai1Laboratory of Synaptic Development and Plasticity, Institute of Life Science and School of Life Sciences, Nanchang University, Nanchang, Jiangxi China.
Suqi Zou1Laboratory of Synaptic Development and Plasticity, Institute of Life Science and School of Life Sciences, Nanchang University, Nanchang, Jiangxi China.
Shunqi Wang1Laboratory of Synaptic Development and Plasticity, Institute of Life Science and School of Life Sciences, Nanchang University, Nanchang, Jiangxi China.ORCID 0000-0002-4918-6550
Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTransmembrane protein 108 (Tmem108) is a risk gene of psychiatric diseases including schizophrenia, bipolar disorder and major depression disorder. However, the pathophysiological mechanisms of Tmem108 are largely unknown.

resultsHere we investigated the pathophysiological function of Tmem108 in the hippocampal dentate gyrus by using

conclusionsThus, our data suggest that Tmem108 increases adult neurogenesis and plays a complexity role in psychiatric disorders.

Indexed as

Adult neurogenesisBipolar disorderDentate gyrusMajor depression disorderTransmembrane protein 108

Identifiers

PMID30651970
PMCPMC6330398
OpenAlexW2941309557

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.