Evidence map›Paper›PMID 30651931›Full record

ArticleOncotarget2018

The high-sensitivity modified Glasgow prognostic score is superior to the modified Glasgow prognostic score as a prognostic predictor for head and neck cancer.

Nobuhiro Hanai, Michi Sawabe, Takahiro Kimura, Hidenori Suzuki, Taijiro Ozawa, Hitoshi Hirakawa, Yujiro Fukuda, Yasuhisa Hasegawa

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

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  6. Prognostic scores in laryngeal cancer.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Nobuhiro HanaiDepartment of Head and Neck Surgery, Aichi Cancer Center Hospital, Aichi, Japan.
Michi SawabeDepartment of Head and Neck Surgery, Aichi Cancer Center Hospital, Aichi, Japan.
Takahiro KimuraDepartment of Head and Neck Surgery, Aichi Cancer Center Hospital, Aichi, Japan.
Hidenori SuzukiDepartment of Head and Neck Surgery, Aichi Cancer Center Hospital, Aichi, Japan.
Taijiro OzawaDepartment of Head and Neck Surgery, Aichi Cancer Center Hospital, Aichi, Japan.
Hitoshi HirakawaDepartment of Head and Neck Surgery, Aichi Cancer Center Hospital, Aichi, Japan.
Yujiro FukudaDepartment of Head and Neck Surgery, Aichi Cancer Center Hospital, Aichi, Japan.
Yasuhisa HasegawaDepartment of Head and Neck Surgery, Aichi Cancer Center Hospital, Aichi, Japan.
Aichi Cancer Center · JPAsahi University · JPToyohashi Municipal Hospital · JPUniversity of the Ryukyus · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is increasing evidence that the inflammatory indices of modified Glasgow prognostic score (mGPS) and high-sensitivity mGPS (HS-mGPS) play important roles in predicting the survival in many cancer; however, evidence supporting such an association in head and neck cancer (HNC) is scarce. MATERIALS AND

methodsWe evaluated the impact of the mGPS and HS-mGPS on the overall survival (OS) in 129 patients with HNC treated at Aichi Cancer Center Central Hospital from 2012-2013. The mGPS was calculated as follows: mGPS of 0, C-reactive protein (CRP) ≤1.0 mg/dl; 1, CRP >1.0 mg/dl; 2, CRP>1.0 mg/dl and albumin <3.5 mg/dl. Regarding the HS-mGPS, the CRP threshold level was set as 0.3 mg/dl. Hazard ratios (HRs) and 95% confidence intervals (95% CIs) were estimated by Cox proportional hazard models after adjusting for potential confounders.

resultsThe prognosis of HNC worsened significantly as both the mGPS and HS-mGPS increased in a univariate analysis. After adjusting for covariates, the HS-mGPS was significantly associated with the OS (adjusted HR for HS-mGPS of 2 compared to an HS-mGPS of 0 [HR

conclusionWe conclude that the HS-mGPS is useful as an independent prognostic factor in HNC.

Indexed as

C-reactive proteinhead and neck cancerhigh-sensitivity modified Glasgow prognostic scoremodified Glasgow prognostic scoresurvival

Identifiers

PMID30651931
PMCPMC6319335
OpenAlexW2904890049

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.