ReviewChild and adolescent psychiatry and mental health2019
The effects of parental opioid use on the parent-child relationship and children's developmental and behavioral outcomes: a systematic review of published reports.
Review in Child and adolescent psychiatry and mental health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- Impact of exposure to opioids in pregnancy on offspring developmental outcomes in the preschool years: an umbrella review.BMJ paediatrics open · 2025Pooled it
- Parental drug use disorders and youth psychopathology: Meta-analytic review.Drug and alcohol dependence · 2023Pooled it
- Effect of E-learning clinical management of substance-dependent pregnant women on the knowledge and clinical skill performance of midwives: a randomized controlled trial.BMC pregnancy and childbirth · 2025Trial
- Optimizing Opioid Use in Pain Management: A Comprehensive Review of Clinical Benefits, Risks, and Dependence.Healthcare (Basel, Switzerland) · 2026Review
- Are Parent Substance Use Severity and Psychopathology Associated with Parenting Behaviors Among Parents with Substance Use Disorders?Parenting, science and practice · 2026Article
- The Socioeconomic Impact of Long-Acting Injectable Buprenorphine.ClinicoEconomics and outcomes research : CEOR · 2026Article
- From morphine to buprenorphine - Modeling opioid use disorder and its treatment during pregnancy: Effects on maternal care and offspring neurodevelopment in a translational rodent model.Pharmacology, biochemistry, and behavior · 2025Article
- Parental Opioid Misuse and Adolescent-Reported Positive Parenting Behaviors: An Analysis of Parent-Child Dyads From the National Survey on Drug Use and Health.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025Article
- Parenting through the eyes of mothers with substance use disorder: Implications for treatment and related services.Drug and alcohol dependence · 2025Article
- Early School Medicaid Expansions and Health Services for Children With Parental Opioid Use Disorder.JAMA health forum · 2025Article
- Maternal alcohol dependence symptoms, maternal insensitivity to children's distress, and young children's blunted emotional reactivity.Development and psychopathology · 2025Article
- Needs and Challenges to Improve Rehabilitative Care for Parents with Substance Use Disorder - A Qualitative Study from the Expert's Perspective.Substance abuse and rehabilitation · 2025Article
- Paternal addiction to cigarettes, alcohol, and opium and the psychological distress of their youths in southeast Iran.Scientific reports · 2024Article
- Impact of opioid overdoses on US life expectancy and years of life lost, by demographic group and stimulant co-involvement: a mortality data analysis from 2019 to 2022.Lancet regional health. Americas · 2024Article
- Foster Care and Health in Medicaid-Enrolled Children Experiencing Parental Opioid Use Disorder.JAMA network open · 2024Article
- Article
- Maternal Substance Use and Early-Life Adversity: Inducing Drug Dependence in Offspring, Interactions, Mechanisms, and Treatments.Addiction & health · 2024Review
- Article
- "I've smoked weed with my daughter": Cannabis Use within Families Affected by Parental Opioid Misuse.Children and youth services review · 2023Article
- Preconception care, prenatal care, and postpartum bonding in women with substance use.Heliyon · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundBetween 2009 and 2014, nearly 3% of US children (age ≤ 17 years) lived in households with at least 1 parent with substance use disorder. The present systematic review aimed to evaluate effects of parental opioid use disorder on the parent-child relationship and child developmental and behavioral outcomes.
methodsSeveral databases were comprehensively searched for studies published from January 1980 through February 2018 that reviewed effects of parental opioid addiction on parent-child relationships and outcomes of children (age, 0-16 years).
resultsOf 304 unique studies, 12 evaluated effects of parental opioid addiction on the parent-child relationship as the primary outcome and on children's outcomes, including behaviors and development. Observation of mother-child interaction showed that mothers with opioid use disorders are more irritable, ambivalent, and disinterested while showing greater difficulty interpreting children's cues compared with the control group. Children of parents with opioid use disorders showed greater disorganized attachment; they were less likely to seek contact and more avoidant than children in the control group. The children also had increased risk of emotional and behavioral issues, poor academic performance, and poor social skills. Younger children had increased risk of abuse or neglect, or both, that later in life may lead to such difficulties as unemployment, legal issues, and substance abuse.
conclusionsCurrent evidence shows association between parental opioid addiction and poorer mother-child attachment and suboptimal child developmental and behavioral outcomes. Further research and treatment targeting children and families with parental opioid use are needed to prevent difficulties later in life.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.