Evidence map›Paper›PMID 30651682›Full record

ReviewJournal of oral and maxillofacial pathology : JOMFP

Stem-cell therapy and platelet-rich plasma in regenerative medicines: A review on pros and cons of the technologies.

Shwetha Hulimavu Ramaswamy Reddy, Roopa Reddy, N Chaitanya Babu, G N Ashok

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of oral and maxillofacial pathology : JOMFP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Overview of Available Treatments and Their Limitations for Hypertrophic Facet Joints-A Systematic Review of the Literature.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Platelet-rich plasma for pilonidal disease: a systematic review.The Journal of international medical research · 2023
    Pooled it
  7. Pooled it
  8. Clinical management of alveolar osteitis. A systematic review.Medicina oral, patologia oral y cirugia bucal · 2021
    Pooled it
  9. Pooled it
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Osteonecrosis of the femoral head: treatment before the collapse. Experience with decompression and biological therapy.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Article
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shwetha Hulimavu Ramaswamy ReddyDepartment of Oral Pathology, MMNG Halgekar Institute of Dental Science, Belagavi, Karnataka, India.
Roopa ReddyCenter for Incubation, Innovation, Research and Consultancy, Jyothy Institute of Technology, Bengaluru, Karnataka, India.
N Chaitanya BabuDepartment of Oral Pathologist, Chaitanya Dental Clinic, Bengaluru, Karnataka, India.
G N AshokGeneral and Laparoscopic Surgeon, SSNMC Hospital, Bengaluru, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regenerative medicine encompasses new emerging branch of medical sciences that involves the functional restoration of tissues or organs caused by severe injuries or chronic diseases. Currently, there are two contending technologies that can repair and restore the damaged tissues, namely platelet-rich plasma (PRP)- and stem cell (SC)-based therapies. PRP is a component of blood that contains platelet concentrations above the normal level and includes platelet-related growth factors and plasma-derived fibrinogen. Platelets are the frontline healing response to injuries as they release growth factors for tissue repair. SCs, on the other hand, are the unspecialized, undifferentiated, immature cells that based on specific stimuli can divide and differentiate into specific type of cells and tissues. Differentiated SCs can divide and replace the worn out or damaged tissues to become tissue- or organ-specific cells with specialized functions. Despite these differences, both approaches rely on rejuvenating the damaged tissue. This review is focused on delineating the preparation procedures, similarities and disparities and advantages and disadvantages of PRP- and SC-based therapies.

Indexed as

Platelet-rich plasmaregenerationstem cellstreatment

Identifiers

PMID30651682
PMCPMC6306612

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.