Evidence map›Paper›PMID 30651638›Full record

ArticleNature2019

Interacting neural ensembles in orbitofrontal cortex for social and feeding behaviour.

Joshua H Jennings, Christina K Kim, James H Marshel, Misha Raffiee, Li Ye, Sean Quirin, Sally Pak, Charu Ramakrishnan, Karl Deisseroth

Abstract read
In one paragraph

Article in Nature, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers.

0numbers the graph read from it
0cells of the map it votes in
121citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

121 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Optogenetic Hedonic Hotspots in the Orbitofrontal Cortex and Insula: Causing Enhancement of Sweetness "Liking".The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  5. Timing and Convergence of Ensemble Activity Govern Auditory Thalamocortical Transmission.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

61 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Joshua H JenningsDepartment of Bioengineering, Stanford University, Stanford, CA, USA.
Christina K KimNeurosciences Program, Stanford University, Stanford, CA, USA.
James H MarshelDepartment of Bioengineering, Stanford University, Stanford, CA, USA.
Misha RaffieeDepartment of Bioengineering, Stanford University, Stanford, CA, USA.
Li YeDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Sean QuirinDepartment of Bioengineering, Stanford University, Stanford, CA, USA.
Sally PakDepartment of Bioengineering, Stanford University, Stanford, CA, USA.
Charu RamakrishnanDepartment of Bioengineering, Stanford University, Stanford, CA, USA.
Karl DeisserothDepartment of Bioengineering, Stanford University, Stanford, CA, USA. deissero@stanford.edu.

Funding

Channel Structure-Based Tools for Precise Interrogation of Circuitry and BehaviorR37MH075957 · NIMH · STANFORD UNIVERSITY · PI DEISSEROTH, KARL A. · 2013 to 2022
$7.3M
Structural and molecular identification of circuitry underlying joint processing of motivation and aversionR37DA035377 · NIDA · STANFORD UNIVERSITY · PI DEISSEROTH, KARL A. · 2013 to 2022
$6.2M
Brain-wide functional mapping of circuits controlling hedonic feeding in obesityK01DK114165 · NIDDK · STANFORD UNIVERSITY · PI YE, LI · 2017 to 2021
$825k
Top-down regulation of compulsive reward-seeking behavior by medial prefrontal cortexF31DA041795 · NIDA · STANFORD UNIVERSITY · PI KIM, CHRISTINA · 2016 to 2017
$52k
Howard Hughes Medical InstituteNIDA NIH HHS F31 DA041795NIDA NIH HHS R37 DA035377NIDDK NIH HHS K01 DK114165NIMH NIH HHS R37 MH075957
6 · The paper itself

Abstract

Categorically distinct basic drives (for example, for social versus feeding behaviour

Indexed as

Social BehaviorAnimalsConditioning, OperantEnergy IntakeFeeding BehaviorMaleMiceMice, Inbred C57BLNeural PathwaysNeuronsOptogeneticsPrefrontal CortexRewardSingle-Cell Analysis

Identifiers

PMID30651638
PMCPMC6447429

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.