Evidence map›Paper›PMID 30651633›Full record

ArticleLeukemia2019

ASXL1 alteration cooperates with JAK2V617F to accelerate myelofibrosis.

Ying Guo, Yuan Zhou, Shohei Yamatomo, Hui Yang, Peng Zhang, Shi Chen, Stephen D Nimer, Zhizhuang Joe Zhao, Mingjiang Xu, Jie Bai and 1 more

Abstract readLetter
PubMed Publisher
In one paragraph

Article in Leukemia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Review
  3. The Role and Impact of Non-driver Gene Mutations in Myelofibrosis.Current hematologic malignancy reports · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Epigenetic regulation by ASXL1 in myeloid malignancies.International journal of hematology · 2023
    Review
  9. Article
  10. Haematologica · 2023
    Article
  11. Article
  12. ASXL1/2 mutations and myeloid malignancies.Journal of hematology & oncology · 2022
    Review
  13. Article
  14. Article
  15. Article
  16. Epigenetic Dysregulation of Myeloproliferative Neoplasms.Hematology/oncology clinics of North America · 2021
    Review
  17. Review
  18. The Molecular Genetics of Myeloproliferative Neoplasms.Cold Spring Harbor perspectives in medicine · 2020
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ying Guo *Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Yuan Zhou *State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.
Shohei YamatomoSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Hui YangSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Peng ZhangSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Shi ChenSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Stephen D NimerSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Zhizhuang Joe ZhaoDepartment of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Mingjiang XuSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Jie BaiState Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China. janebai86@hotmail.com.
Feng-Chun YangSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA. fxy37@med.miami.edu.

Funding

Role of Asxl1 in normal hematopoiesis and pathogenesis of myeloid malignanciesR01CA172408 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI XU, MINGJIANG, YANG, FENG-CHUN · 2014 to 2024
$3.4M
NCI NIH HHS R01 CA172408
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Epistasis, GeneticGene Expression RegulationGenetic Predisposition to DiseaseMutationAmino Acid SubstitutionDisease ProgressionHumansJanus Kinase 2Primary MyelofibrosisPrognosisRepressor ProteinsASXL1 protein, humanJAK2 protein, humanJanus Kinase 2Repressor Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.