Evidence map›Paper›PMID 30651423›Full record

ReviewKorean journal of pediatrics2019

A perspective on partially hydrolyzed protein infant formula in nonexclusively breastfed infants.

Yvan Vandenplas, Zakiudin Munasir, Badriul Hegar, Dewi Kumarawati, Ahmad Suryawan, Muzal Kadim, Julistio Tb Djais, Ray Wagiu Basrowi, Deni Krisnamurti

Open access · diamondAbstract readReview
In one paragraph

Review in Korean journal of pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Yvan VandenplasKidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel, Brussel, Belgium.
Zakiudin MunasirDepartment of Child Health, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Badriul HegarDepartment of Child Health, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Dewi KumarawatiDepartment of Child Health, Udayana University Medical School/Sanglah Hospital, Denpasar, Indonesia.
Ahmad SuryawanDepartment of Child Health, Medical School, Unviersity of Airlangga, Surabaya, Indonesia.
Muzal KadimDepartment of Child Health, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Julistio Tb DjaisDepartment of Child Health, Medical School, University of Padjadjaran, Bandung, Indonesia.
Ray Wagiu BasrowiNestle Nutrition Institute, Jakarta, Indonesia.
Deni KrisnamurtiNestle Nutrition Institute, Jakarta, Indonesia.
University of Indonesia · IDAirlangga University · IDPadjadjaran University · IDUdayana University · IDVrije Universiteit Brussel · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The World Health Organization recommends that infants should be exclusively breastfed for the first 6 months of life to provide optimal nutrition in this critical period of life. After this, infants should receive nutritionally adequate and safe complementary foods while breastfeeding continues for up to 2 years of age or beyond. For nonbreastfed infants, infant formula is an available option to provide the nutrition needed. Infant formula is usually prepared from industrially modified cow's milk and processed to adjust for the nutritional needs of infants. However, cow's milk is one of the most common causes of food allergy, affecting 2%-5% of all formula-fed infants during their first year of life. One strategy to prevent cow's milk allergy in nonbreastfed infants is the use of partially hydrolyzed formula (pHF) in high-risk infants, which are infants born in families with atopic disease. However, based on an epidemiological study, approximately half of the infants who develop allergy are not part of the at-risk group. This is because the non-at-risk group is significantly larger than the at-risk group and the non-at-risk infants have approximately 15% risk of developing allergies. This study aimed to evaluate the effects of partially hydrolyzed whey formula (pHF-W) in nonbreastfed infants and determine whether pHF-W can prevent atopic disease in high-risk infants and can be used as routine starter formula regardless of the allergy risk status.

Indexed as

BreastfeedingCow’s milk protein allergyFormula feedingHydrolysateInfant feedingPartial hydrolysate

Identifiers

PMID30651423
PMCPMC6528056
OpenAlexW2910617977

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.