Evidence map›Paper›PMID 30651396›Full record

ArticleJournal of clinical microbiology2019

Vaccination of Icelandic Children with the 10-Valent Pneumococcal Vaccine Leads to a Significant Herd Effect among Adults in Iceland.

Sigríður J Quirk, Gunnsteinn Haraldsson, Martha Á Hjálmarsdóttir, Andries J van Tonder, Birgir Hrafnkelsson, Stephen D Bentley, Ásgeir Haraldsson, Helga Erlendsdóttir, Angela B Brueggemann, Karl G Kristinsson

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Journal of clinical microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Disease Trends and Mortality From Invasive Pneumococcal Disease: A Long-Term Population-Based Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Carbon Source-Dependent Changes of the Structure ofInternational journal of molecular sciences · 2021
    Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Sigríður J QuirkUniversity of Iceland, Faculty of Medicine, Reykjavík, Iceland.
Gunnsteinn HaraldssonUniversity of Iceland, Faculty of Medicine, Reykjavík, Iceland.
Martha Á HjálmarsdóttirUniversity of Iceland, Faculty of Medicine, Reykjavík, Iceland.
Andries J van TonderParasites and Microbes, Wellcome Sanger Institute, Hinxton, United Kingdom.
Birgir HrafnkelssonUniversity of Iceland, Department of Mathematics, Reykjavík, Iceland.
Stephen D BentleyParasites and Microbes, Wellcome Sanger Institute, Hinxton, United Kingdom.
Ásgeir HaraldssonUniversity of Iceland, Faculty of Medicine, Reykjavík, Iceland.
Helga ErlendsdóttirUniversity of Iceland, Faculty of Medicine, Reykjavík, Iceland.
Angela B BrueggemannNuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Karl G KristinssonUniversity of Iceland, Faculty of Medicine, Reykjavík, Iceland karl@landspitali.is.
National University Hospital of Iceland · ISUniversity of Iceland · ISWellcome Sanger Institute · GBImperial College London · GBReykjavík University · IS

Funding

Wellcome TrustWellcome Trust 04992/Z/14/ZWellcome Trust 083511/Z/07/Z
6 · The paper itself

Abstract

The introduction of pneumococcal conjugate vaccines (PCVs) into childhood vaccination programs has reduced carriage of vaccine serotypes and pneumococcal disease. The 10-valent PCV was introduced in Iceland in 2011. The aim of this study was to determine PCV impact on the prevalence of serotypes, genetic lineages, and antimicrobial-resistant pneumococci isolated from the lower respiratory tract (LRT) of adults. Pneumococci isolated between 2009 and 2017 at the Landspitali University Hospital were included (

Indexed as

AdolescentAdultAnti-Bacterial AgentsHumansIcelandImmunity, HerdMicrobial Sensitivity TestsMiddle AgedMultilocus Sequence TypingNasopharynxPneumococcal VaccinesPneumonia, PneumococcalSerogroupStreptococcus pneumoniaeVaccinationYoung Adult10-valent pneumococcal vaccineAnti-Bacterial AgentsPneumococcal VaccinesadultsepidemiologyIcelandlower respiratory tractmolecular epidemiologypneumococcuspneumoniaStreptococcus pneumoniaevaccination

Identifiers

PMID30651396
PMCPMC6440763
OpenAlexW2910842647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.