Evidence map›Paper›PMID 30651312›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Feeding state sculpts a circuit for sensory valence in

Sophie Rengarajan, Kristen A Yankura, Manon L Guillermin, Wendy Fung, Elissa A Hallem

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
  2. Hungry for Knowledge: Octopamine Signaling Regulates Hunger-Enhanced Olfactory Learning.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. The dopaminergic system ofRoyal Society open science · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Thermosensory behaviors of the free-living life stages ofbioRxiv : the preprint server for biology · 2024
    Article
  11. Review
  12. Article
  13. Outcrossing inEcology and evolution · 2024
    Article
  14. Article
  15. Review
  16. Article
  17. Differential processing of a chemosensory cue across life stages sharing the same valence state inProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Review
  19. Multisensory Integration inBrain sciences · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sophie RengarajanDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA 90095.
Kristen A YankuraDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA 90095.
Manon L GuillerminDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA 90095.
Wendy FungDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA 90095.
Elissa A HallemDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA 90095 ehallem@ucla.edu.
University of California, Los Angeles · US

Funding

UCLA-Caltech Medical Scientist Training ProgramT32GM008042 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AJIJOLA, OLUJIMI A, DAWSON, DAVID WAYNE · 1985 to 2023
$29.9M
UCLA NIGMS T32 Program AssessmentT32GM007185 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TORRES, JORGE · 1985 to 2020
$21.7M
Training Program in Neural MicrocircuitsT32NS058280 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FELDMAN, JACK L · 2007 to 2017
$2.4M
Dopaminergic modulation of CO2 response during starvation in C. elegansF30GM116810 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RENGARAJAN, SOPHIE · 2015 to 2017
$114k
Howard Hughes Medical InstituteNIGMS NIH HHS F30 GM116810NIGMS NIH HHS T32 GM007185NIGMS NIH HHS T32 GM008042NINDS NIH HHS T32 NS058280
6 · The paper itself

Abstract

Hunger affects the behavioral choices of all animals, and many chemosensory stimuli can be either attractive or repulsive depending on an animal's hunger state. Although hunger-induced behavioral changes are well documented, the molecular and cellular mechanisms by which hunger modulates neural circuit function to generate changes in chemosensory valence are poorly understood. Here, we use the CO

Indexed as

AnimalsBiogenic AminesCaenorhabditis elegansCarbon DioxideDopamineFeeding BehaviorInterneuronsNematodaOctopamineSensory Receptor CellsSignal TransductionStarvationBiogenic AminesCarbon DioxideDopamineOctopaminebiogenic aminescarbon dioxideC. eleganssensory valencestarvation

Identifiers

PMID30651312
PMCPMC6358703
OpenAlexW2909311857

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.