ArticleGenes2019
A Direct Comparison of the Relationship of Epigenetic Aging and Epigenetic Substance Consumption Markers to Mortality in the Framingham Heart Study.
Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Intervention effects on self-control decrease speed of biological aging mediated by changes in substance use: A longitudinal study of African American youth.Family process · 2022Trial
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- Differing Effects of Alcohol Use on Epigenetic and Brain Age in Adult Children of Parents with Alcohol Use Disorder.Brain sciences · 2024Article
- Heavy alcohol consumption but not smoking predicts mortality in patients with acute coronary syndrome.Epigenetics · 2024Article
- Article
- Digital methylation assessments of alcohol and cigarette consumption account for common variance in accelerated epigenetic ageing.Epigenetics · 2022Article
- Article
- The association between DNA methylation of 6p21.33 and AHRR in blood and coronary heart disease in Chinese population.BMC cardiovascular disorders · 2022Article
- Article
- The relationship of smoking to cg05575921 methylation in blood and saliva DNA samples from several studies.Scientific reports · 2021Article
- A simple, rapid, interpretable, actionable and implementable digital PCR based mortality index.Epigenetics · 2021Article
- A DNA methylation clock associated with age-related illnesses and mortality is accelerated in men with combat PTSD.Molecular psychiatry · 2021Article
- Hypomethylation ofGenes · 2021Article
- Childhood adversity is linked to adult health among African Americans via adolescent weight gain and effects are genetically moderated.Development and psychopathology · 2021Article
- Article
- Bacteria-related changes in host DNA methylation and the risk for CRC.Gut microbes · 2020Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
A number of studies have examined the relationship of indices of epigenetic aging (EA) to key health outcomes. Unfortunately, our understanding of the relationship of EA to mortality and substance use-related health variables is unclear. In order to clarify these interpretations, we analyzed the relationship of the Levine EA index (LEA), as well as established epigenetic indices of cigarette (cg05575921) and alcohol consumption (cg04987734), to all-cause mortality in the Framingham Heart Study Offspring Cohort (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.