Evidence map›Paper›PMID 30650646›Full record

ArticleMolecules (Basel, Switzerland)2019

Involvement of the Hydroperoxy Group in the Irreversible Inhibition of Leukocyte-Type 12-Lipoxygenase by Monoterpene Glycosides Contained in the Qing Shan Lu Shui Tea.

Yuki Kawakami, Akemi Otsuki, Yoshiko Mori, Keita Kanzaki, Toshiko Suzuki-Yamamoto, Ding Zhi Fang, Hideyuki Ito, Yoshitaka Takahashi

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Monoterpenoid Glycosides from the Leaves ofMolecules (Basel, Switzerland) · 2023
    Article
  3. Article
  4. Chemical Constituents from the Leaves ofMolecules (Basel, Switzerland) · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Yuki KawakamiDepartment of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197, Japan. kawaka@fhw.oka-pu.ac.jp.
Akemi OtsukiDepartment of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197, Japan. okapu.1222041akemi@gmail.com.
Yoshiko MoriDepartment of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197, Japan. tyche55cbm@gmail.com.
Keita KanzakiDepartment of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197, Japan. keita.kanzaki@mw.kawasaki-m.ac.jp.
Toshiko Suzuki-YamamotoDepartment of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197, Japan. toshiko@fhw.oka-pu.ac.jp.ORCID 0000-0002-0331-9872
Ding Zhi FangDepartment of Biochemistry and Molecular Biology, West China School of Preclinical and Forensic Medicine, Sichuan University, 17 Section 3, South Renmin Road, Chengdu 610041, China. dzfang@scu.edu.cn.
Hideyuki ItoDepartment of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197, Japan. hito@fhw.oka-pu.ac.jp.
Yoshitaka TakahashiDepartment of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197, Japan. ytaka@fhw.oka-pu.ac.jp.
Okayama Prefectural University · JPSichuan University · CN

Funding

Japan Society for the Promotion of Science 23700916
6 · The paper itself

Abstract

We have previously found two novel monoterpene glycosides, liguroside A and liguroside B, with an inhibitory effect on the catalytic activity of the enzyme leukocyte-type 12-lipoxygenase in the Qing Shan Lu Shui tea. Here, two new monoterpene glycosides, liguroside C and liguroside D which inhibit this enzyme, were isolated from the same tea. The spectral and chemical evidence characterized the structures of these compounds as (5

Indexed as

Arachidonate 12-LipoxygenaseDose-Response Relationship, DrugGlycosidesLeukocytesLipoxygenase InhibitorsMagnetic Resonance SpectroscopyMolecular StructureMonoterpenesPlant ExtractsTeaArachidonate 12-LipoxygenaseGlycosidesLipoxygenase InhibitorsMonoterpenesPlant ExtractsTeahydroperoxy groupirreversible inhibitionleukocyte-type 12-lipoxygenaseligurosideLigustrum robustummonoterpene glycosideQing Shan Lu Shui

Identifiers

PMID30650646
PMCPMC6358863
OpenAlexW2910234125

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.