Evidence map›Paper›PMID 30650570›Full record

ArticleViruses2019

Clinical Characterization of Host Response to Simian Hemorrhagic Fever Virus Infection in Permissive and Refractory Hosts: A Model for Determining Mechanisms of VHF Pathogenesis.

Joseph P Cornish, Ian N Moore, Donna L Perry, Abigail Lara, Mahnaz Minai, Dominique Promeneur, Katie R Hagen, Kimmo Virtaneva, Monica Paneru, Connor R Buechler and 9 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 1 country.

Joseph P CornishEmerging Viral Pathogens Section, Laboratory of Immunoregulation, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 8200 Research Plaza, Fort Detrick, Frederick, MD 21702, USA. joseph.cornish@nih.gov.
Ian N MooreInfectious Disease Pathogenesis Section, Comparative Medicine Branch, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 12735 Twinbrook Parkway, Rockville, MD 20852, USA. Ian.Moore@NIH.gov.
Donna L PerryIntegrated Research Facility, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 8200 Research Plaza, Fort Detrick, Frederick, MD 21702, USA. donna.perry@NIH.gov.
Abigail LaraIntegrated Research Facility, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 8200 Research Plaza, Fort Detrick, Frederick, MD 21702, USA. laraa@MedImmune.com.
Mahnaz MinaiInfectious Disease Pathogenesis Section, Comparative Medicine Branch, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 12735 Twinbrook Parkway, Rockville, MD 20852, USA. minaim@niaid.nih.gov.
Dominique PromeneurIntegrated Research Facility, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 8200 Research Plaza, Fort Detrick, Frederick, MD 21702, USA. dominique.promeneur@nih.gov.
Katie R HagenIntegrated Research Facility, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 8200 Research Plaza, Fort Detrick, Frederick, MD 21702, USA. katie.hagen@nih.gov.
Kimmo VirtanevaGenomics Unit, Research Technologies Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South 4th Street, Hamilton, MT 59840, USA. kvirtaneva@niaid.nih.gov.
Monica PaneruGenomics Unit, Research Technologies Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South 4th Street, Hamilton, MT 59840, USA. monica.paneru@nih.gov.
Connor R BuechlerDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, 3170 UW Medical Foundation Centennial Building, 1685 Highland Ave, Madison, WI 53711, USA. connor.buechler@gmail.com.
David H O'ConnorDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, 3170 UW Medical Foundation Centennial Building, 1685 Highland Ave, Madison, WI 53711, USA. dhoconno@wisc.edu.ORCID 0000-0003-2139-470X
Adam L BaileyDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, 3170 UW Medical Foundation Centennial Building, 1685 Highland Ave, Madison, WI 53711, USA. adam.bailey@wustl.edu.ORCID 0000-0002-6560-9680
Kurt CooperIntegrated Research Facility, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 8200 Research Plaza, Fort Detrick, Frederick, MD 21702, USA. kurt.cooper@nih.gov.
Steven MazurIntegrated Research Facility, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 8200 Research Plaza, Fort Detrick, Frederick, MD 21702, USA. steven.mazur@nih.gov.
John G BernbaumIntegrated Research Facility, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 8200 Research Plaza, Fort Detrick, Frederick, MD 21702, USA. bernbaumjg@niaid.nih.gov.
James PettittIntegrated Research Facility, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 8200 Research Plaza, Fort Detrick, Frederick, MD 21702, USA. james.d.pettitt@gmail.com.
Peter B JahrlingEmerging Viral Pathogens Section, Laboratory of Immunoregulation, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 8200 Research Plaza, Fort Detrick, Frederick, MD 21702, USA. jahrlingp@niaid.nih.gov.
Jens H KuhnIntegrated Research Facility, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 8200 Research Plaza, Fort Detrick, Frederick, MD 21702, USA. kuhnjens@niaid.nih.gov.ORCID 0000-0002-7800-6045
Reed F JohnsonEmerging Viral Pathogens Section, Laboratory of Immunoregulation, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 8200 Research Plaza, Fort Detrick, Frederick, MD 21702, USA. johnsonreed@niaid.nih.gov.
National Institutes of Health · USUniversity of Wisconsin–Madison · US

Funding

Integrated Research Facility at Fort DetrickZICAI009006 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI DONAHUE, SARAH · 2019 to 2025
$332.9M
INTEGRATED TRAINING FOR PHYSICIAN-SCIENTISTST32GM008692 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BURKARD, MARK E · 1998 to 2020
$10.3M
Division of Clinical Research, National Institute of Allergy and Infectious Diseases N/ADivision of Intramural Research, National Institute of Allergy and Infectious Diseases N/ANIGMS NIH HHS T32 GM008692
6 · The paper itself

Abstract

Simian hemorrhagic fever virus (SHFV) causes a fulminant and typically lethal viral hemorrhagic fever (VHF) in macaques (Cercopithecinae:

Indexed as

Host-Pathogen InteractionsAnimalsAntibodies, ViralArterivirusArterivirus InfectionsCytokinesErythrocebusFemaleHemorrhagic Fevers, ViralMacacaMacrophagesMaleMonkey DiseasesRNA, ViralVirus ReplicationAntibodies, ViralCytokinesRNA, ViralArteriviridaearterivirushost responsemacaquepatas monkeypathogenesisSHFVsimarterivirussimian hemorrhagic feverviral hemorrhagic fever

Identifiers

PMID30650570
PMCPMC6356329
OpenAlexW2899210735

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.