Evidence map›Paper›PMID 30650550›Full record

ReviewInternational journal of molecular sciences2019

Evolution of Disease Defense Genes and Their Regulators in Plants.

Rongzhi Zhang, Fengya Zheng, Shugen Wei, Shujuan Zhang, Genying Li, Peijian Cao, Shancen Zhao

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
7.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Genomic Insights into Cobweb Disease Resistance inJournal of fungi (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Article
  7. NopAA and NopD Signaling Association-Related GeneInternational journal of molecular sciences · 2023
    Article
  8. Different responses of two maize cultivars toFrontiers in plant science · 2023
    Article
  9. Review
  10. Article
  11. Chromosomal-level genome of velvet bean (Mucuna pruriens) provides resources for L-DOPA synthetic research and development.DNA research : an international journal for rapid publication of reports on genes and genomes · 2022
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Rongzhi ZhangInstitute of Crop Science, Shandong Academy of Agricultural Sciences, Key Laboratory of Wheat Biology & Genetic Improvement on North Yellow & Huai River Valley, Ministry of Agriculture, National Engineering Laboratory for Wheat & Maize, Jinan 250100, China. zhangrongzhi1981@126.com.
Fengya ZhengBGI Institute of Applied Agriculture, BGI-Agro, Shenzhen 518083, China. zhengfengya@genomics.cn.
Shugen WeiGuangxi Botanical Garden of Medicinal Plants, Nanning 530023, China. weishugen2@163.com.
Shujuan ZhangInstitute of Crop Science, Shandong Academy of Agricultural Sciences, Key Laboratory of Wheat Biology & Genetic Improvement on North Yellow & Huai River Valley, Ministry of Agriculture, National Engineering Laboratory for Wheat & Maize, Jinan 250100, China. zsjhappy@163.com.
Genying LiInstitute of Crop Science, Shandong Academy of Agricultural Sciences, Key Laboratory of Wheat Biology & Genetic Improvement on North Yellow & Huai River Valley, Ministry of Agriculture, National Engineering Laboratory for Wheat & Maize, Jinan 250100, China. lgy111@126.com.
Peijian CaoChina Tobacco Gene Research Center, Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou 450001, China. PeijianCao@163.com.ORCID 0000-0001-9991-423X
Shancen ZhaoBGI Institute of Applied Agriculture, BGI-Agro, Shenzhen 518083, China. zhaoshancen@genomics.cn.
Shandong Academy of Agricultural Sciences · CNBGI Group (China) · CNChina Tobacco · CNGuangxi Medicinal Botanical Garden · CN

Funding

Natural Science Foundation of Shandong Province; National Natural Science Foundation of China; Agricultural Science and Technology Innovation Project of Shandong Academy of Agricultural Sciences; he Youth Talent Program of Shandong Academy of Agricultural ZR2014CM006; 31501312, 31401378 and 31601301; CXGC2016C09; 2014QNZ02
6 · The paper itself

Abstract

Biotic stresses do damage to the growth and development of plants, and yield losses for some crops. Confronted with microbial infections, plants have evolved multiple defense mechanisms, which play important roles in the never-ending molecular arms race of plant⁻pathogen interactions. The complicated defense systems include pathogen-associated molecular patterns (PAMP) triggered immunity (PTI), effector triggered immunity (ETI), and the exosome-mediated cross-kingdom RNA interference (CKRI) system. Furthermore, plants have evolved a classical regulation system mediated by miRNAs to regulate these defense genes. Most of the genes/small RNAs or their regulators that involve in the defense pathways can have very rapid evolutionary rates in the longitudinal and horizontal co-evolution with pathogens. According to these internal defense mechanisms, some strategies such as molecular switch for the disease resistance genes, host-induced gene silencing (HIGS), and the new generation of RNA-based fungicides, have been developed to control multiple plant diseases. These broadly applicable new strategies by transgene or spraying ds/sRNA may lead to reduced application of pesticides and improved crop yield.

Indexed as

Evolution, MolecularGenes, PlantDisease ResistanceMicroRNAsPlant DiseasesStress, PhysiologicalMicroRNAsCKRIdisease resistance geneETIHIGSmiRNA regulationPTISIGS

Identifiers

PMID30650550
PMCPMC6358896
OpenAlexW2911014050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.