Evidence map›Paper›PMID 30650119›Full record

ArticlePloS one2019

Trends in the risk of myocardial infarction among HIV-1-infected individuals relative to the general population in France: Impact of gender and immune status.

Aliou Baldé, Sylvie Lang, Aline Wagner, Jean Ferrières, Michèle Montaye, Pierre Tattevin, Laurent Cotte, Elisabeth Aslangul, Frédéric Bidégain, Antoine Chéret and 7 more

Abstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Cardiovascular disease risk in women living with HIV.Current opinion in HIV and AIDS · 2022
    Review
  8. Review
  9. HIV and cardiovascular disease.The lancet. HIV · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Aliou BaldéSorbonne Université, INSERM, Institut Pierre Louis d'épidémiologie et de Santé Publique, IPLESP, Paris, France.ORCID 0000-0001-5956-698X
Sylvie LangSorbonne Université, INSERM, Institut Pierre Louis d'épidémiologie et de Santé Publique, IPLESP, Paris, France.
Aline WagnerLaboratoire d'épidémiologie et de santé publique, Université de Strasbourg, Strasbourg, France.
Jean FerrièresCentre hospitalier universitaire de Rangueil, service de cardiologie B, Université de Toulouse, Toulouse, France.
Michèle MontayeINSERM, Institut Pasteur de Lille, Univ. Lille, CHU Lille, France.
Pierre TattevinHôpital Universitaire Pontchaillou, service des maladies infectieuses et USI, Rennes, France.
Laurent CotteINSERM U1052, Hospices Civils de Lyon, Hôpital de la Croix Rousse, service des maladies infectieuses et tropicales, Lyon, France.
Elisabeth AslangulSorbonne Paris Cité, Université Paris Descartes, APHP, Hôtel Dieu, service de médecine interne, Paris, France.
Frédéric BidégainAPHP, Hôpital Avicenne, service de maladie infectieuse, Bobigny, France.
Antoine ChéretSorbonne Paris Cité, Université Paris Descartes, Paris, Centre hospitalier de Tourcoing, service des maladies infectieuses, Tourcoing, France.
Murielle Mary-KrauseSorbonne Université, INSERM, Institut Pierre Louis d'épidémiologie et de Santé Publique, IPLESP, Paris, France.
Jean-Luc MeynardAPHP, Hôpital Saint-Antoine, service des maladies infectieuses et tropicales, Paris, France.
Jean-Michel MolinaSorbonne Paris Cité, Université de Paris Diderot Paris, INSERM, UMRS 941, APHP, Hôpital Saint-Louis, service des maladies infectieuses et tropicales, Paris, France.
Marialuisa PartisaniHôpitaux Universitaires de Strasbourg, Le Trait D'Union, centre de soins de l'infection par le VIH, Strasbourg, France.
Pierre-Marie RogerUniversité de Nice Sophia-Antipolis, Centre hospitalier universitaire de Nice, groupe hospitalier l'Archet, service d'infectiologie, Nice, France.
Franck BoccaraSorbonne Université, INSERM, APHP, Hôpital Saint-Antoine, service de cardiologie, Paris, France.
Dominique CostagliolaSorbonne Université, INSERM, Institut Pierre Louis d'épidémiologie et de Santé Publique, IPLESP, Paris, France.

Funding

HIV and Mycobacterial Disease in MaliD43TW010350 · FIC · UNIV OF SCIENCES, TECH & TECH OF BAMAKO · PI MAIGA, ALMOUSTAPHA ISSIAKA, MURPHY, ROBERT LEO · 2016 to 2025
$3.0M
Northwestern University AITRPD43TW007995 · FIC · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MURPHY, ROBERT LEO · 2008 to 2012
$1.6M
FIC NIH HHS D43 TW007995FIC NIH HHS D43 TW010350
6 · The paper itself

Abstract

We examined trends in the MI incidence and age at MI diagnosis among adults living with HIV-1 between 2000 and 2009, by comparison with the French MI registries, by gender. Age standardized incidence rates and standardized incidence-ratios (SIRs) were estimated for individuals included in the French hospital database on HIV (n = 71 204, MI = 663) during three periods: 2000-2002, 2003-2005 and 2006-2009. Median ages at MI diagnosis were compared using the Brown-Mood test. Over the study periods, the absolute rate difference and relative risks were higher in women than in men in 2000-2002 and 2006-2009, with respective SIRs 1.99 (1.39-2.75) and 1.12 (0.99-1.27) in 2006-2009. The trends were different for men and women with a decreasing trend in SIRs in men and no change in women. In both sexes, among individuals with CD4 ≥500/μL and controlled viral-load on cART, the risk was no longer elevated. Age at MI diagnosis was significantly younger than in the general population, especially among women (-6.2 years, p<0.001; men: -2.1 years, p = 0.02). In HIV-1-positive adults, absolute rate difference and relative risks and trends of MI were different between men and women and there was no additional risk among individuals on effective cART.

Indexed as

HIV-1AdultAge FactorsAnti-HIV AgentsDatabases, FactualFemaleFranceHIV InfectionsHumansIncidenceMaleMiddle AgedMyocardial InfarctionRisk FactorsSex FactorsViral LoadAnti-HIV Agents

Identifiers

PMID30650119
PMCPMC6334967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.