Evidence map›Paper›PMID 30649895›Full record

ArticleAmerican journal of respiratory and critical care medicine2019

Alveolar Macrophage Apoptosis-associated Bacterial Killing Helps Prevent Murine Pneumonia.

Julie A Preston, Martin A Bewley, Helen M Marriott, A McGarry Houghton, Mohammed Mohasin, Jamil Jubrail, Lucy Morris, Yvonne L Stephenson, Simon Cross, David R Greaves and 8 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. RACK1 promotes the development and function of alveolar macrophages through directly binding to and stabilizing PPARγ.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Review
  9. Leukocyte kinetics and bacterial clearance duringAmerican journal of physiology. Lung cellular and molecular physiology · 2025
    Article
  10. Review
  11. Review
  12. Review
  13. Cell Death and Infection: Implications for Host and Microbe.Advances in experimental medicine and biology · 2025
    Review
  14. Article
  15. Necroptosis in bacterial infections.Frontiers in immunology · 2024
    Review
  16. Innate immune responses in pneumonia.Pneumonia (Nathan Qld.) · 2023
    Review
  17. Transient increase in atherosclerotic plaque macrophage content followingFrontiers in cellular and infection microbiology · 2023
    Article
  18. Article
  19. Article
  20. Multiplatform Single-Cell Analysis Identifies Immune Cell Types Enhanced in Pulmonary Fibrosis.American journal of respiratory cell and molecular biology · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 10 institutions in 7 countries.

Julie A Preston1 The Florey Institute for Host-Pathogen Interactions and.
Martin A Bewley1 The Florey Institute for Host-Pathogen Interactions and.
Helen M Marriott1 The Florey Institute for Host-Pathogen Interactions and.
A McGarry Houghton3 Clinical Research Division, Fred Hutchinson Cancer Research Center, and.
Mohammed Mohasin5 Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka, Bangladesh.
Jamil Jubrail6 MRC Centre for Inflammation Research.
Lucy Morris1 The Florey Institute for Host-Pathogen Interactions and.
Yvonne L Stephenson1 The Florey Institute for Host-Pathogen Interactions and.
Simon Cross1 The Florey Institute for Host-Pathogen Interactions and.
David R Greaves8 Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Ruth W Craig9 Department of Pharmacology and Toxicology, Geissel School of Medicine at Dartmouth, Hanover, New Hampshire.
Nico van Rooijen10 Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, the Netherlands.
Colin D Bingle1 The Florey Institute for Host-Pathogen Interactions and.
Robert C Read11 University of Southampton Medical School, Southampton, United Kingdom.
Timothy J Mitchell13 Institute of Microbiology and Infection, School of Immunity and Infection, University of Birmingham, Birmingham, United Kingdom; and.
Moira K B Whyte6 MRC Centre for Inflammation Research.
Steven D Shapiro15 Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
David H Dockrell6 MRC Centre for Inflammation Research.ORCID 0000-0002-2718-4861
Florey Institute of Neuroscience and Mental Health · AUCentre for Inflammation Research · GBAmsterdam UMC Location Vrije Universiteit Amsterdam · NLCape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa · ZADartmouth College · USInstitute of Infection and Immunity · CANational Institute for Health Research · GBUniversity of Dhaka · BDUniversity of Oxford · GBUniversity of Pittsburgh Medical Center · US

Funding

British Heart Foundation RG/15/10/31485Medical Research Council MR/M017931/1Medical Research Council MR/N013204/1Medical Research Council MR/N026993/1Medical Research Council MR/N02995X/1Wellcome TrustWellcome Trust 076945
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Pneumonia, BacterialAnimalsApoptosisBacteriaBiphenyl CompoundsCaspasesClodronic AcidDisease Models, AnimalHaemophilus influenzaeHumansMacrophages, AlveolarMiceMice, TransgenicMitochondriaMyeloid Cell Leukemia Sequence 1 ProteinNitric OxideABT-737Biphenyl CompoundsCaspasesClodronic AcidMCL1 protein, humanMyeloid Cell Leukemia Sequence 1 ProteinNitric OxideNitrophenolsPiperazinesReactive Oxygen SpeciesSulfonamidesapoptosisbacteriamacrophageMcl-1pneumonia

Identifiers

PMID30649895
PMCPMC6603058
OpenAlexW2909285912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.