Article3D printing in medicine2018
3D printing of surgical hernia meshes impregnated with contrast agents: in vitro proof of concept with imaging characteristics on computed tomography.
Article in 3D printing in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- To infinity and beyond: the promise of data-driven 3D printing of hernia mesh - a primer for surgeons.Hernia : the journal of hernias and abdominal wall surgery · 2025Review
- Preparation of surgical meshes using self-regulating technology based on reaction-diffusion processes.Medical & biological engineering & computing · 2024Article
- From Meshes to Minimally Invasive Techniques: A Comprehensive Review of Modern Hernia Repair Approaches.Cureus · 2024Review
- A Review of Abdominal Meshes for Hernia Repair-Current Status and Emerging Solutions.Materials (Basel, Switzerland) · 2023Review
- Reverse Engineering and 3D Printing of Medical Devices for Drug Delivery and Drug-Embedded Anatomic Implants.Polymers · 2023Review
- Novel Material Optimization Strategies for Developing Upgraded Abdominal Meshes.International journal of molecular sciences · 2023Review
- X-Ray Markers for Thin Film Implants.Advanced healthcare materials · 2022Article
- Preparation and Biocompatibility Study of Contrast-Enhanced Hernia Mesh Material.Tissue engineering and regenerative medicine · 2022Article
- New Insights into the Application of 3D-Printing Technology in Hernia Repair.Materials (Basel, Switzerland) · 2021Review
- 3D-Printing of Drug-Eluting Implants: An Overview of the Current Developments Described in the Literature.Molecules (Basel, Switzerland) · 2021Review
- A calibration CT mini-lung-phantom created by 3-D printing and subtractive manufacturing.Journal of applied clinical medical physics · 2021Article
- Article
- 3D Printing of Drug-Loaded Thermoplastic Polyurethane Meshes: A Potential Material for Soft Tissue Reinforcement in Vaginal Surgery.Pharmaceutics · 2020Article
- Antibiotics in 3D-printed implants, instruments and materials: benefits, challenges and future directions.Journal of 3D printing in medicine · 2019Review
- 3D Printing Custom Bioactive and Absorbable Surgical Screws, Pins, and Bone Plates for Localized Drug Delivery.Journal of functional biomaterials · 2019Article
- 3D Printing for Bio-Synthetic Biliary Stents.Bioengineering (Basel, Switzerland) · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundSelected medical implants and other 3D printed constructs could potentially benefit from the ability to incorporate contrast agents into their structure. The purpose of the present study is to create 3D printed surgical meshes impregnated with iodinated, gadolinium, and barium contrast agents and characterize their computed tomography (CT) imaging characteristics. Commercial fused deposition layering 3D printing was used to construct surgical meshes impregnated with imaging contrast agents in an in vitro model. Polycaprolactone (PCL) meshes were printed containing iodinated, gadolinium, or barium contrast; control PCL meshes without contrast were also fabricated. The three different contrast agents were mixed with PCL powder and directly loaded into the 3D printer. CT images of the three contrast-containing meshes and the control meshes were acquired and analyzed using small elliptical regions of interest to record the Hounsfield units (HU) of each mesh. Subsequently, to test their solubility and sustainability, the contrast-containing meshes were placed in a 37 °C agar solution for 7 days and imaged by CT at days 1, 3 and 7.
resultsAll 3D printed meshes were visible on CT. Iodinated contrast meshes had the highest attenuation (2528 mean HU), significantly higher than both and gadolinium (1178 mean HU) and barium (592 mean HU) containing meshes. Only barium meshes sustained their visibility in the agar solution; the iodine and gadolinium meshes were poorly perceptible and had significantly lower mean HU compared to their pre-agar solution imaging, with iodine and gadolinium present in the adjacent agar at day 7 CT.
conclusion3D prints embedded with contrast materials through this method displayed excellent visibility on CT; however, only barium mesh maintained visibility after 7 days incubation on agar at human body temperature. This method of 3D printing with barium may have potential applications in a variety of highly personalized and CT visible medical devices.
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Registered trials
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